LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 SB590885
0.04
uM
LJP5
 72
hr
 1235 4598 4513 1.0188 1.0258
MDA-MB-231 PIK-93
0.04
uM
LJP5
 72
hr
 1235 4444 4513 0.9847 0.9790
MDA-MB-231 KIN001-043
0.04
uM
LJP6
 72
hr
 1235 3783 4513 0.8382 0.7772
MDA-MB-231 Alpelisib
0.04
uM
LJP5
 72
hr
 1235 4387 4513 0.9720 0.9615
MDA-MB-231 Luminespib
0.04
uM
LJP5
 72
hr
 1235 847 4513 0.1877 -0.1187
MDA-MB-231 A443654
0.04
uM
LJP6
 72
hr
 1235 3529 4513 0.7819 0.6996
MDA-MB-231 OSI-027
0.04
uM
LJP6
 72
hr
 1235 4518 4513 1.0011 1.0015
MDA-MB-231 XMD11-85h
0.04
uM
LJP6
 72
hr
 1235 3707 4513 0.8213 0.7539
MDA-MB-231 HG-6-64-01
0.04
uM
LJP6
 72
hr
 1235 3983 4513 0.8825 0.8382
MDA-MB-231 WH-4-025
0.04
uM
LJP5
 72
hr
 1235 3774 4513 0.8363 0.7745
MDA-MB-231 WZ-4-145
0.04
uM
LJP6
 72
hr
 1235 3498 4513 0.7751 0.6903
MDA-MB-231 XMD16-144
0.04
uM
LJP5
 72
hr
 1235 1465 4513 0.3247 0.0700
MDA-MB-231 Brivanib
0.04
uM
LJP5
 72
hr
 1235 4067 4513 0.9011 0.8637
MDA-MB-231 Buparlisib
0.04
uM
LJP5
 72
hr
 1235 4633 4513 1.0265 1.0365
MDA-MB-231 BX-912
0.04
uM
LJP5
 72
hr
 1235 4297 4513 0.9522 0.9341
MDA-MB-231 Canertinib
0.04
uM
LJP6
 72
hr
 1235 4465 4513 0.9893 0.9853
MDA-MB-231 Celastrol
0.04
uM
LJP6
 72
hr
 1235 5069 4513 1.1232 1.1696
MDA-MB-231 CGP60474
0.04
uM
LJP5
 72
hr
 1235 3304 4513 0.7321 0.6311
MDA-MB-231 CGP60474
0.04
uM
LJP6
 72
hr
 1235 534 4513 0.1183 -0.2142
MDA-MB-231 CHIR-99021
0.04
uM
LJP6
 72
hr
 1235 3927 4513 0.8700 0.8210
MDA-MB-231 CP724714
0.04
uM
LJP5
 72
hr
 1235 4774 4513 1.0577 1.0794
MDA-MB-231 CP466722
0.04
uM
LJP5
 72
hr
 1235 4695 4513 1.0403 1.0555
MDA-MB-231 Crizotinib
0.04
uM
LJP5
 72
hr
 1235 4502 4513 0.9974 0.9965
MDA-MB-231 Momelotinib
0.04
uM
LJP5
 72
hr
 1235 4092 4513 0.9067 0.8715
MDA-MB-231 Dasatinib
0.04
uM
LJP5
 72
hr
 1235 2691 4513 0.5962 0.4439