LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 BI-2536
0.37
uM
LJP6
 72
hr
 1235 1015 4513 0.2250 -0.0672
MDA-MB-231 BMS345541
0.37
uM
LJP6
 72
hr
 1235 3687 4513 0.8170 0.7480
MDA-MB-231 SNS-032
0.37
uM
LJP6
 72
hr
 1235 489 4513 0.1083 -0.2279
MDA-MB-231 GDC-0980
0.37
uM
LJP5
 72
hr
 1235 2022 4513 0.4480 0.2398
MDA-MB-231 NVP-AEW541
0.37
uM
LJP5
 72
hr
 1235 4603 4513 1.0199 1.0275
MDA-MB-231 SB590885
0.37
uM
LJP5
 72
hr
 1235 4197 4513 0.9299 0.9034
MDA-MB-231 PIK-93
0.37
uM
LJP5
 72
hr
 1235 4209 4513 0.9325 0.9071
MDA-MB-231 KIN001-043
0.37
uM
LJP6
 72
hr
 1235 3573 4513 0.7916 0.7130
MDA-MB-231 Alpelisib
0.37
uM
LJP5
 72
hr
 1235 4274 4513 0.9469 0.9269
MDA-MB-231 Luminespib
0.37
uM
LJP5
 72
hr
 1235 833 4513 0.1846 -0.1228
MDA-MB-231 A443654
0.37
uM
LJP6
 72
hr
 1235 726 4513 0.1609 -0.1556
MDA-MB-231 OSI-027
0.37
uM
LJP6
 72
hr
 1235 3706 4513 0.8211 0.7537
MDA-MB-231 XMD11-85h
0.37
uM
LJP6
 72
hr
 1235 3933 4513 0.8715 0.8231
MDA-MB-231 HG-6-64-01
0.37
uM
LJP6
 72
hr
 1235 1998 4513 0.4428 0.2327
MDA-MB-231 WH-4-025
0.37
uM
LJP5
 72
hr
 1235 1296 4513 0.2871 0.0183
MDA-MB-231 WZ-4-145
0.37
uM
LJP6
 72
hr
 1235 3218 4513 0.7131 0.6049
MDA-MB-231 XMD16-144
0.37
uM
LJP5
 72
hr
 1235 1462 4513 0.3239 0.0690
MDA-MB-231 Brivanib
0.37
uM
LJP5
 72
hr
 1235 4187 4513 0.9276 0.9003
MDA-MB-231 Buparlisib
0.37
uM
LJP5
 72
hr
 1235 3987 4513 0.8835 0.8395
MDA-MB-231 BX-912
0.37
uM
LJP5
 72
hr
 1235 2132 4513 0.4724 0.2735
MDA-MB-231 Canertinib
0.37
uM
LJP6
 72
hr
 1235 4023 4513 0.8915 0.8505
MDA-MB-231 Celastrol
0.37
uM
LJP6
 72
hr
 1235 3589 4513 0.7953 0.7181
MDA-MB-231 CGP60474
0.37
uM
LJP5
 72
hr
 1235 521 4513 0.1154 -0.2181
MDA-MB-231 CGP60474
0.37
uM
LJP6
 72
hr
 1235 459 4513 0.1017 -0.2370
MDA-MB-231 CHIR-99021
0.37
uM
LJP6
 72
hr
 1235 3731 4513 0.8267 0.7613