LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 TGX221
0.12
uM
LJP5
 72
hr
 1235 4117 4513 0.9123 0.8792
MDA-MB-231 Torin1
0.12
uM
LJP6
 72
hr
 1235 1985 4513 0.4399 0.2286
MDA-MB-231 Torin2
0.12
uM
LJP5
 72
hr
 1235 1291 4513 0.2860 0.0168
MDA-MB-231 Tozasertib
0.12
uM
LJP5
 72
hr
 1235 1317 4513 0.2919 0.0248
MDA-MB-231 Trametinib
0.12
uM
LJP5
 72
hr
 1235 1273 4513 0.2820 0.0113
MDA-MB-231 TWS119
0.12
uM
LJP5
 72
hr
 1235 4211 4513 0.9330 0.9078
MDA-MB-231 Vemurafenib
0.12
uM
LJP5
 72
hr
 1235 4648 4513 1.0299 1.0412
MDA-MB-231 Withaferin A
0.12
uM
LJP5
 72
hr
 1235 4923 4513 1.0907 1.1249
MDA-MB-231 Withaferin A
0.12
uM
LJP6
 72
hr
 1235 4250 4513 0.9416 0.9196
MDA-MB-231 WYE-125132
0.12
uM
LJP6
 72
hr
 1235 1684 4513 0.3732 0.1368
MDA-MB-231 WZ3105
0.12
uM
LJP5
 72
hr
 1235 471 4513 0.1044 -0.2333
MDA-MB-231 XMD11-50
0.12
uM
LJP6
 72
hr
 1235 3405 4513 0.7544 0.6618
MDA-MB-231 Y39983
0.12
uM
LJP6
 72
hr
 1235 3402 4513 0.7539 0.6611
MDA-MB-231 YM 201636
0.12
uM
LJP5
 72
hr
 1235 4204 4513 0.9316 0.9057
MDA-MB-231 ZSTK474
0.12
uM
LJP6
 72
hr
 1235 3522 4513 0.7804 0.6976
MDA-MB-231 Afatinib
0.37
uM
LJP6
 72
hr
 1235 3577 4513 0.7926 0.7144
MDA-MB-231 Sigma A6730
0.37
uM
LJP5
 72
hr
 1235 4453 4513 0.9866 0.9816
MDA-MB-231 Alvocidib
0.37
uM
LJP6
 72
hr
 1235 470 4513 0.1041 -0.2337
MDA-MB-231 AT-7519
0.37
uM
LJP6
 72
hr
 1235 496 4513 0.1100 -0.2257
MDA-MB-231 AZD 5438
0.37
uM
LJP6
 72
hr
 1235 1811 4513 0.4014 0.1757
MDA-MB-231 AZD-6482
0.37
uM
LJP5
 72
hr
 1235 3974 4513 0.8806 0.8356
MDA-MB-231 AZD7762
0.37
uM
LJP6
 72
hr
 1235 1162 4513 0.2574 -0.0226
MDA-MB-231 AZD8055
0.37
uM
LJP6
 72
hr
 1235 1857 4513 0.4115 0.1896
MDA-MB-231 AZD8330
0.37
uM
LJP5
 72
hr
 1235 1404 4513 0.3111 0.0513
MDA-MB-231 Barasertib
0.37
uM
LJP5
 72
hr
 1235 1541 4513 0.3416 0.0933