LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 AZD-6482
3.33
uM
LJP5
 72
hr
 1235 3381 4513 0.7491 0.6544
MDA-MB-231 AZD7762
3.33
uM
LJP6
 72
hr
 1235 497 4513 0.1102 -0.2254
MDA-MB-231 AZD8055
3.33
uM
LJP6
 72
hr
 1235 1317 4513 0.2919 0.0249
MDA-MB-231 AZD8330
3.33
uM
LJP5
 72
hr
 1235 1359 4513 0.3011 0.0375
MDA-MB-231 Barasertib
3.33
uM
LJP5
 72
hr
 1235 1444 4513 0.3201 0.0637
MDA-MB-231 BI-2536
3.33
uM
LJP6
 72
hr
 1235 1091 4513 0.2418 -0.0441
MDA-MB-231 BMS345541
3.33
uM
LJP6
 72
hr
 1235 1832 4513 0.4059 0.1819
MDA-MB-231 SNS-032
3.33
uM
LJP6
 72
hr
 1235 530 4513 0.1174 -0.2154
MDA-MB-231 GDC-0980
3.33
uM
LJP5
 72
hr
 1235 1550 4513 0.3435 0.0959
MDA-MB-231 NVP-AEW541
3.33
uM
LJP5
 72
hr
 1235 4489 4513 0.9946 0.9926
MDA-MB-231 SB590885
3.33
uM
LJP5
 72
hr
 1235 3806 4513 0.8433 0.7842
MDA-MB-231 PIK-93
3.33
uM
LJP5
 72
hr
 1235 3867 4513 0.8567 0.8027
MDA-MB-231 KIN001-043
3.33
uM
LJP6
 72
hr
 1235 3354 4513 0.7432 0.6464
MDA-MB-231 Alpelisib
3.33
uM
LJP5
 72
hr
 1235 4249 4513 0.9414 0.9193
MDA-MB-231 Luminespib
3.33
uM
LJP5
 72
hr
 1235 796 4513 0.1764 -0.1342
MDA-MB-231 A443654
3.33
uM
LJP6
 72
hr
 1235 414 4513 0.0917 -0.2508
MDA-MB-231 OSI-027
3.33
uM
LJP6
 72
hr
 1235 2665 4513 0.5906 0.4362
MDA-MB-231 XMD11-85h
3.33
uM
LJP6
 72
hr
 1235 3577 4513 0.7926 0.7144
MDA-MB-231 HG-6-64-01
3.33
uM
LJP6
 72
hr
 1235 1018 4513 0.2256 -0.0664
MDA-MB-231 WH-4-025
3.33
uM
LJP5
 72
hr
 1235 880 4513 0.1951 -0.1084
MDA-MB-231 WZ-4-145
3.33
uM
LJP6
 72
hr
 1235 2486 4513 0.5508 0.3814
MDA-MB-231 XMD16-144
3.33
uM
LJP5
 72
hr
 1235 1180 4513 0.2615 -0.0170
MDA-MB-231 Brivanib
3.33
uM
LJP5
 72
hr
 1235 4181 4513 0.9264 0.8986
MDA-MB-231 Buparlisib
3.33
uM
LJP5
 72
hr
 1235 1350 4513 0.2992 0.0349
MDA-MB-231 BX-912
3.33
uM
LJP5
 72
hr
 1235 1343 4513 0.2976 0.0328