LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 Canertinib
3.33
uM
LJP6
 72
hr
 1235 2468 4513 0.5469 0.3760
MDA-MB-231 Celastrol
3.33
uM
LJP6
 72
hr
 1235 780 4513 0.1728 -0.1391
MDA-MB-231 CGP60474
3.33
uM
LJP5
 72
hr
 1235 448 4513 0.0994 -0.2402
MDA-MB-231 CGP60474
3.33
uM
LJP6
 72
hr
 1235 292 4513 0.0647 -0.2880
MDA-MB-231 CHIR-99021
3.33
uM
LJP6
 72
hr
 1235 3725 4513 0.8254 0.7596
MDA-MB-231 CP724714
3.33
uM
LJP5
 72
hr
 1235 4353 4513 0.9644 0.9510
MDA-MB-231 CP466722
3.33
uM
LJP5
 72
hr
 1235 3791 4513 0.8400 0.7796
MDA-MB-231 Crizotinib
3.33
uM
LJP5
 72
hr
 1235 1421 4513 0.3148 0.0565
MDA-MB-231 Momelotinib
3.33
uM
LJP5
 72
hr
 1235 1339 4513 0.2967 0.0315
MDA-MB-231 Dasatinib
3.33
uM
LJP5
 72
hr
 1235 671 4513 0.1488 -0.1722
MDA-MB-231 Dasatinib
3.33
uM
LJP6
 72
hr
 1235 627 4513 0.1391 -0.1856
MDA-MB-231 Dovitinib
3.33
uM
LJP5
 72
hr
 1235 1938 4513 0.4295 0.2144
MDA-MB-231 Enzastaurin
3.33
uM
LJP5
 72
hr
 1235 4809 4513 1.0654 1.0901
MDA-MB-231 Erlotinib
3.33
uM
LJP5
 72
hr
 1235 4459 4513 0.9880 0.9835
MDA-MB-231 Foretinib
3.33
uM
LJP5
 72
hr
 1235 1122 4513 0.2487 -0.0347
MDA-MB-231 R406
3.33
uM
LJP6
 72
hr
 1235 3183 4513 0.7053 0.5941
MDA-MB-231 Pictilisib
3.33
uM
LJP6
 72
hr
 1235 2904 4513 0.6435 0.5091
MDA-MB-231 Gefitinib
3.33
uM
LJP6
 72
hr
 1235 4163 4513 0.9224 0.8931
MDA-MB-231 Geldanamycin
3.33
uM
LJP5
 72
hr
 1235 743 4513 0.1647 -0.1503
MDA-MB-231 Geldanamycin
3.33
uM
LJP6
 72
hr
 1235 596 4513 0.1321 -0.1951
MDA-MB-231 GSK1059615
3.33
uM
LJP5
 72
hr
 1235 1118 4513 0.2477 -0.0360
MDA-MB-231 GSK1059615
3.33
uM
LJP6
 72
hr
 1235 1188 4513 0.2632 -0.0146
MDA-MB-231 GSK1904529A
3.33
uM
LJP6
 72
hr
 1235 4370 4513 0.9683 0.9564
MDA-MB-231 Omipalisib
3.33
uM
LJP6
 72
hr
 1235 824 4513 0.1826 -0.1256
MDA-MB-231 GSK 690693
3.33
uM
LJP5
 72
hr
 1235 4823 4513 1.0686 1.0945