LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 Selumetinib
1.11
uM
LJP6
 72
hr
 1235 2705 4513 0.5993 0.4482
MDA-MB-231 Sirolimus
1.11
uM
LJP6
 72
hr
 1235 3535 4513 0.7833 0.7016
MDA-MB-231 Sorafenib
1.11
uM
LJP6
 72
hr
 1235 4641 4513 1.0282 1.0389
MDA-MB-231 SU11274
1.11
uM
LJP5
 72
hr
 1235 4176 4513 0.9253 0.8972
MDA-MB-231 Fedratinib
1.11
uM
LJP5
 72
hr
 1235 2577 4513 0.5711 0.4094
MDA-MB-231 TGX221
1.11
uM
LJP5
 72
hr
 1235 4311 4513 0.9551 0.9382
MDA-MB-231 Torin1
1.11
uM
LJP6
 72
hr
 1235 1541 4513 0.3415 0.0932
MDA-MB-231 Torin2
1.11
uM
LJP5
 72
hr
 1235 956 4513 0.2120 -0.0852
MDA-MB-231 Tozasertib
1.11
uM
LJP5
 72
hr
 1235 1351 4513 0.2995 0.0353
MDA-MB-231 Trametinib
1.11
uM
LJP5
 72
hr
 1235 1305 4513 0.2891 0.0211
MDA-MB-231 TWS119
1.11
uM
LJP5
 72
hr
 1235 3605 4513 0.7987 0.7228
MDA-MB-231 Vemurafenib
1.11
uM
LJP5
 72
hr
 1235 4371 4513 0.9684 0.9565
MDA-MB-231 Withaferin A
1.11
uM
LJP5
 72
hr
 1235 1003 4513 0.2222 -0.0711
MDA-MB-231 Withaferin A
1.11
uM
LJP6
 72
hr
 1235 978 4513 0.2168 -0.0785
MDA-MB-231 WYE-125132
1.11
uM
LJP6
 72
hr
 1235 1697 4513 0.3760 0.1407
MDA-MB-231 WZ3105
1.11
uM
LJP5
 72
hr
 1235 446 4513 0.0989 -0.2409
MDA-MB-231 XMD11-50
1.11
uM
LJP6
 72
hr
 1235 2134 4513 0.4729 0.2741
MDA-MB-231 Y39983
1.11
uM
LJP6
 72
hr
 1235 2999 4513 0.6646 0.5381
MDA-MB-231 YM 201636
1.11
uM
LJP5
 72
hr
 1235 3223 4513 0.7141 0.6063
MDA-MB-231 ZSTK474
1.11
uM
LJP6
 72
hr
 1235 2846 4513 0.6307 0.4914
MDA-MB-231 Afatinib
3.33
uM
LJP6
 72
hr
 1235 2749 4513 0.6090 0.4616
MDA-MB-231 Sigma A6730
3.33
uM
LJP5
 72
hr
 1235 4244 4513 0.9403 0.9178
MDA-MB-231 Alvocidib
3.33
uM
LJP6
 72
hr
 1235 447 4513 0.0992 -0.2405
MDA-MB-231 AT-7519
3.33
uM
LJP6
 72
hr
 1235 283 4513 0.0628 -0.2905
MDA-MB-231 AZD 5438
3.33
uM
LJP6
 72
hr
 1235 594 4513 0.1317 -0.1958