LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 Nintedanib
1.11
uM
LJP6
 72
hr
 1235 4282 4513 0.9488 0.9294
MDA-MB-231 NU7441
1.11
uM
LJP5
 72
hr
 1235 4212 4513 0.9333 0.9082
MDA-MB-231 Dactolisib
1.11
uM
LJP5
 72
hr
 1235 1357 4513 0.3006 0.0369
MDA-MB-231 NVP-TAE684
1.11
uM
LJP6
 72
hr
 1235 1814 4513 0.4019 0.1764
MDA-MB-231 Palbociclib
1.11
uM
LJP6
 72
hr
 1235 2231 4513 0.4944 0.3037
MDA-MB-231 PD0325901
1.11
uM
LJP5
 72
hr
 1235 1295 4513 0.2869 0.0180
MDA-MB-231 PD0325901
1.11
uM
LJP6
 72
hr
 1235 1069 4513 0.2369 -0.0508
MDA-MB-231 PD173074
1.11
uM
LJP6
 72
hr
 1235 4916 4513 1.0893 1.1230
MDA-MB-231 PD184352
1.11
uM
LJP5
 72
hr
 1235 3376 4513 0.7480 0.6530
MDA-MB-231 Pelitinib
1.11
uM
LJP5
 72
hr
 1235 3138 4513 0.6952 0.5803
MDA-MB-231 PF431396
1.11
uM
LJP5
 72
hr
 1235 1535 4513 0.3402 0.0913
MDA-MB-231 PF477736
1.11
uM
LJP5
 72
hr
 1235 2190 4513 0.4853 0.2913
MDA-MB-231 PF562271
1.11
uM
LJP6
 72
hr
 1235 2354 4513 0.5216 0.3412
MDA-MB-231 PHA-665752
1.11
uM
LJP5
 72
hr
 1235 4645 4513 1.0291 1.0401
MDA-MB-231 PHA-793887
1.11
uM
LJP6
 72
hr
 1235 924 4513 0.2048 -0.0951
MDA-MB-231 PI103
1.11
uM
LJP6
 72
hr
 1235 1835 4513 0.4066 0.1829
MDA-MB-231 PLX-4720
1.11
uM
LJP5
 72
hr
 1235 4404 4513 0.9757 0.9666
MDA-MB-231 QL-X-138
1.11
uM
LJP6
 72
hr
 1235 2766 4513 0.6128 0.4668
MDA-MB-231 QL-XII-47
1.11
uM
LJP6
 72
hr
 1235 1211 4513 0.2683 -0.0076
MDA-MB-231 Radicicol
1.11
uM
LJP5
 72
hr
 1235 1004 4513 0.2224 -0.0708
MDA-MB-231 Radicicol
1.11
uM
LJP6
 72
hr
 1235 1180 4513 0.2614 -0.0171
MDA-MB-231 Seliciclib
1.11
uM
LJP5
 72
hr
 1235 4116 4513 0.9121 0.8789
MDA-MB-231 Ruxolitinib
1.11
uM
LJP5
 72
hr
 1235 4119 4513 0.9127 0.8798
MDA-MB-231 XL147
1.11
uM
LJP5
 72
hr
 1235 5016 4513 1.1114 1.1535
MDA-MB-231 Saracatinib
1.11
uM
LJP6
 72
hr
 1235 2835 4513 0.6281 0.4879