LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 Radicicol
10.0
uM
LJP6
 72
hr
 1235 833 4513 0.1846 -0.1229
MDA-MB-231 Seliciclib
10.0
uM
LJP5
 72
hr
 1235 2463 4513 0.5458 0.3745
MDA-MB-231 Ruxolitinib
10.0
uM
LJP5
 72
hr
 1235 2267 4513 0.5023 0.3146
MDA-MB-231 XL147
10.0
uM
LJP5
 72
hr
 1235 4168 4513 0.9235 0.8947
MDA-MB-231 Saracatinib
10.0
uM
LJP6
 72
hr
 1235 2083 4513 0.4616 0.2585
MDA-MB-231 Selumetinib
10.0
uM
LJP6
 72
hr
 1235 1577 4513 0.3495 0.1042
MDA-MB-231 Sirolimus
10.0
uM
LJP6
 72
hr
 1235 3274 4513 0.7254 0.6219
MDA-MB-231 Sorafenib
10.0
uM
LJP6
 72
hr
 1235 3819 4513 0.8463 0.7883
MDA-MB-231 SU11274
10.0
uM
LJP5
 72
hr
 1235 1156 4513 0.2561 -0.0244
MDA-MB-231 Fedratinib
10.0
uM
LJP5
 72
hr
 1235 398 4513 0.0882 -0.2557
MDA-MB-231 TGX221
10.0
uM
LJP5
 72
hr
 1235 4077 4513 0.9033 0.8669
MDA-MB-231 Torin1
10.0
uM
LJP6
 72
hr
 1235 987 4513 0.2187 -0.0759
MDA-MB-231 Torin2
10.0
uM
LJP5
 72
hr
 1235 534 4513 0.1184 -0.2141
MDA-MB-231 Tozasertib
10.0
uM
LJP5
 72
hr
 1235 1261 4513 0.2795 0.0078
MDA-MB-231 Trametinib
10.0
uM
LJP5
 72
hr
 1235 1285 4513 0.2848 0.0152
MDA-MB-231 TWS119
10.0
uM
LJP5
 72
hr
 1235 1299 4513 0.2879 0.0194
MDA-MB-231 Vemurafenib
10.0
uM
LJP5
 72
hr
 1235 2280 4513 0.5051 0.3185
MDA-MB-231 Withaferin A
10.0
uM
LJP5
 72
hr
 1235 604 4513 0.1339 -0.1927
MDA-MB-231 Withaferin A
10.0
uM
LJP6
 72
hr
 1235 593 4513 0.1314 -0.1962
MDA-MB-231 WYE-125132
10.0
uM
LJP6
 72
hr
 1235 1212 4513 0.2686 -0.0072
MDA-MB-231 WZ3105
10.0
uM
LJP5
 72
hr
 1235 702 4513 0.1556 -0.1628
MDA-MB-231 XMD11-50
10.0
uM
LJP6
 72
hr
 1235 1168 4513 0.2588 -0.0207
MDA-MB-231 Y39983
10.0
uM
LJP6
 72
hr
 1235 403 4513 0.0893 -0.2541
MDA-MB-231 YM 201636
10.0
uM
LJP5
 72
hr
 1235 986 4513 0.2186 -0.0761
MDA-MB-231 ZSTK474
10.0
uM
LJP6
 72
hr
 1235 1901 4513 0.4213 0.2031