LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | WZ3105 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 871 | 4223 | 0.2064 | -0.1878 |
| SK-BR-3 | XMD11-50 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 3519 | 4223 | 0.8334 | 0.7506 |
| SK-BR-3 | Y39983 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 4181 | 4223 | 0.9901 | 0.9852 |
| SK-BR-3 | YM 201636 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 4446 | 4223 | 1.0529 | 1.0792 |
| SK-BR-3 | ZSTK474 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 2371 | 4223 | 0.5615 | 0.3437 |
| SK-BR-3 | Afatinib | 0.37 | uM | LJP6 | 72 | hr | 1401 | 1401 | 4223 | 0.3318 | -0.0002 |
| SK-BR-3 | Sigma A6730 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 3559 | 4223 | 0.8428 | 0.7646 |
| SK-BR-3 | Alvocidib | 0.37 | uM | LJP6 | 72 | hr | 1401 | 959 | 4223 | 0.2272 | -0.1566 |
| SK-BR-3 | AT-7519 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 1174 | 4223 | 0.2782 | -0.0804 |
| SK-BR-3 | AZD 5438 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 2355 | 4223 | 0.5577 | 0.3379 |
| SK-BR-3 | AZD-6482 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 3999 | 4223 | 0.9471 | 0.9208 |
| SK-BR-3 | AZD7762 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 1341 | 4223 | 0.3176 | -0.0213 |
| SK-BR-3 | AZD8055 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 1361 | 4223 | 0.3224 | -0.0142 |
| SK-BR-3 | AZD8330 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 3474 | 4223 | 0.8228 | 0.7348 |
| SK-BR-3 | Barasertib | 0.37 | uM | LJP5 | 72 | hr | 1401 | 1290 | 4223 | 0.3055 | -0.0394 |
| SK-BR-3 | BI-2536 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 1380 | 4223 | 0.3269 | -0.0075 |
| SK-BR-3 | BMS345541 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 3697 | 4223 | 0.8755 | 0.8137 |
| SK-BR-3 | SNS-032 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 1121 | 4223 | 0.2656 | -0.0992 |
| SK-BR-3 | GDC-0980 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 1409 | 4223 | 0.3338 | 0.0029 |
| SK-BR-3 | NVP-AEW541 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 3778 | 4223 | 0.8946 | 0.8423 |
| SK-BR-3 | SB590885 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 4685 | 4223 | 1.1095 | 1.1638 |
| SK-BR-3 | PIK-93 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 3898 | 4223 | 0.9230 | 0.8848 |
| SK-BR-3 | KIN001-043 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 3311 | 4223 | 0.7840 | 0.6767 |
| SK-BR-3 | Alpelisib | 0.37 | uM | LJP5 | 72 | hr | 1401 | 3342 | 4223 | 0.7914 | 0.6877 |
| SK-BR-3 | Luminespib | 0.37 | uM | LJP5 | 72 | hr | 1401 | 1584 | 4223 | 0.3752 | 0.0648 |