LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | SB590885 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 4570 | 4223 | 1.0823 | 1.1232 |
| SK-BR-3 | PIK-93 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 3056 | 4223 | 0.7238 | 0.5866 |
| SK-BR-3 | KIN001-043 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 3438 | 4223 | 0.8142 | 0.7219 |
| SK-BR-3 | Alpelisib | 3.33 | uM | LJP5 | 72 | hr | 1401 | 2546 | 4223 | 0.6029 | 0.4056 |
| SK-BR-3 | Luminespib | 3.33 | uM | LJP5 | 72 | hr | 1401 | 1599 | 4223 | 0.3788 | 0.0702 |
| SK-BR-3 | A443654 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 984 | 4223 | 0.2331 | -0.1479 |
| SK-BR-3 | OSI-027 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 1673 | 4223 | 0.3962 | 0.0962 |
| SK-BR-3 | XMD11-85h | 3.33 | uM | LJP6 | 72 | hr | 1401 | 3772 | 4223 | 0.8932 | 0.8401 |
| SK-BR-3 | HG-6-64-01 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 2258 | 4223 | 0.5348 | 0.3037 |
| SK-BR-3 | WH-4-025 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 4040 | 4223 | 0.9567 | 0.9351 |
| SK-BR-3 | WZ-4-145 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 1764 | 4223 | 0.4179 | 0.1287 |
| SK-BR-3 | XMD16-144 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 1623 | 4223 | 0.3843 | 0.0785 |
| SK-BR-3 | Brivanib | 3.33 | uM | LJP5 | 72 | hr | 1401 | 4138 | 4223 | 0.9799 | 0.9698 |
| SK-BR-3 | Buparlisib | 3.33 | uM | LJP5 | 72 | hr | 1401 | 1053 | 4223 | 0.2493 | -0.1235 |
| SK-BR-3 | BX-912 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 1423 | 4223 | 0.3370 | 0.0076 |
| SK-BR-3 | Canertinib | 3.33 | uM | LJP6 | 72 | hr | 1401 | 1395 | 4223 | 0.3304 | -0.0022 |
| SK-BR-3 | Celastrol | 3.33 | uM | LJP6 | 72 | hr | 1401 | 1162 | 4223 | 0.2752 | -0.0848 |
| SK-BR-3 | CGP60474 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 1086 | 4223 | 0.2573 | -0.1116 |
| SK-BR-3 | CGP60474 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 809 | 4223 | 0.1916 | -0.2099 |
| SK-BR-3 | CHIR-99021 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 4000 | 4223 | 0.9473 | 0.9212 |
| SK-BR-3 | CP724714 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 1856 | 4223 | 0.4397 | 0.1613 |
| SK-BR-3 | CP466722 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 3557 | 4223 | 0.8423 | 0.7639 |
| SK-BR-3 | Crizotinib | 3.33 | uM | LJP5 | 72 | hr | 1401 | 2431 | 4223 | 0.5757 | 0.3650 |
| SK-BR-3 | Momelotinib | 3.33 | uM | LJP5 | 72 | hr | 1401 | 2884 | 4223 | 0.6830 | 0.5255 |
| SK-BR-3 | Dasatinib | 3.33 | uM | LJP5 | 72 | hr | 1401 | 3019 | 4223 | 0.7150 | 0.5734 |