LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 PD0325901
0.12
uM
LJP5
 72
hr
 1235 2470 4513 0.5473 0.3766
MDA-MB-231 PD0325901
0.12
uM
LJP6
 72
hr
 1235 2428 4513 0.5379 0.3637
MDA-MB-231 PD173074
0.12
uM
LJP6
 72
hr
 1235 4694 4513 1.0401 1.0552
MDA-MB-231 PD184352
0.12
uM
LJP5
 72
hr
 1235 4050 4513 0.8973 0.8586
MDA-MB-231 Pelitinib
0.12
uM
LJP5
 72
hr
 1235 4532 4513 1.0041 1.0057
MDA-MB-231 PF431396
0.12
uM
LJP5
 72
hr
 1235 3390 4513 0.7511 0.6573
MDA-MB-231 PF477736
0.12
uM
LJP5
 72
hr
 1235 3964 4513 0.8783 0.8324
MDA-MB-231 PF562271
0.12
uM
LJP6
 72
hr
 1235 3386 4513 0.7503 0.6562
MDA-MB-231 PHA-665752
0.12
uM
LJP5
 72
hr
 1235 4659 4513 1.0324 1.0446
MDA-MB-231 PHA-793887
0.12
uM
LJP6
 72
hr
 1235 1698 4513 0.3762 0.1410
MDA-MB-231 PI103
0.12
uM
LJP6
 72
hr
 1235 2668 4513 0.5912 0.4370
MDA-MB-231 PLX-4720
0.12
uM
LJP5
 72
hr
 1235 4456 4513 0.9873 0.9825
MDA-MB-231 QL-X-138
0.12
uM
LJP6
 72
hr
 1235 3854 4513 0.8540 0.7990
MDA-MB-231 QL-XII-47
0.12
uM
LJP6
 72
hr
 1235 2314 4513 0.5127 0.3289
MDA-MB-231 Radicicol
0.12
uM
LJP5
 72
hr
 1235 3425 4513 0.7588 0.6679
MDA-MB-231 Radicicol
0.12
uM
LJP6
 72
hr
 1235 3118 4513 0.6908 0.5742
MDA-MB-231 Seliciclib
0.12
uM
LJP5
 72
hr
 1235 4391 4513 0.9728 0.9626
MDA-MB-231 Ruxolitinib
0.12
uM
LJP5
 72
hr
 1235 4191 4513 0.9285 0.9016
MDA-MB-231 XL147
0.12
uM
LJP5
 72
hr
 1235 4962 4513 1.0993 1.1368
MDA-MB-231 Saracatinib
0.12
uM
LJP6
 72
hr
 1235 3260 4513 0.7224 0.6177
MDA-MB-231 Selumetinib
0.12
uM
LJP6
 72
hr
 1235 3641 4513 0.8067 0.7338
MDA-MB-231 Sirolimus
0.12
uM
LJP6
 72
hr
 1235 3485 4513 0.7721 0.6862
MDA-MB-231 Sorafenib
0.12
uM
LJP6
 72
hr
 1235 4569 4513 1.0123 1.0169
MDA-MB-231 SU11274
0.12
uM
LJP5
 72
hr
 1235 4521 4513 1.0016 1.0022
MDA-MB-231 Fedratinib
0.12
uM
LJP5
 72
hr
 1235 4035 4513 0.8940 0.8541