LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | TGX221 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 3463 | 4223 | 0.8202 | 0.7309 |
| SK-BR-3 | Torin1 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 1894 | 4223 | 0.4486 | 0.1747 |
| SK-BR-3 | Torin2 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 1283 | 4223 | 0.3038 | -0.0420 |
| SK-BR-3 | Tozasertib | 0.04 | uM | LJP5 | 72 | hr | 1401 | 1337 | 4223 | 0.3167 | -0.0228 |
| SK-BR-3 | Trametinib | 0.04 | uM | LJP5 | 72 | hr | 1401 | 3281 | 4223 | 0.7770 | 0.6662 |
| SK-BR-3 | TWS119 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4829 | 4223 | 1.1436 | 1.2150 |
| SK-BR-3 | Vemurafenib | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4553 | 4223 | 1.0783 | 1.1172 |
| SK-BR-3 | Withaferin A | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4170 | 4223 | 0.9876 | 0.9814 |
| SK-BR-3 | Withaferin A | 0.04 | uM | LJP6 | 72 | hr | 1401 | 4473 | 4223 | 1.0592 | 1.0886 |
| SK-BR-3 | WYE-125132 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 1663 | 4223 | 0.3938 | 0.0927 |
| SK-BR-3 | WZ3105 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 905 | 4223 | 0.2144 | -0.1759 |
| SK-BR-3 | XMD11-50 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 3750 | 4223 | 0.8880 | 0.8323 |
| SK-BR-3 | Y39983 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 4244 | 4223 | 1.0050 | 1.0074 |
| SK-BR-3 | YM 201636 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4814 | 4223 | 1.1400 | 1.2095 |
| SK-BR-3 | ZSTK474 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 3262 | 4223 | 0.7725 | 0.6595 |
| SK-BR-3 | Afatinib | 0.12 | uM | LJP6 | 72 | hr | 1401 | 1416 | 4223 | 0.3354 | 0.0052 |
| SK-BR-3 | Sigma A6730 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 3636 | 4223 | 0.8610 | 0.7919 |
| SK-BR-3 | Alvocidib | 0.12 | uM | LJP6 | 72 | hr | 1401 | 964 | 4223 | 0.2284 | -0.1548 |
| SK-BR-3 | AT-7519 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 1469 | 4223 | 0.3479 | 0.0240 |
| SK-BR-3 | AZD 5438 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 3016 | 4223 | 0.7143 | 0.5724 |
| SK-BR-3 | AZD-6482 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 3738 | 4223 | 0.8851 | 0.8281 |
| SK-BR-3 | AZD7762 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 1526 | 4223 | 0.3614 | 0.0441 |
| SK-BR-3 | AZD8055 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 1438 | 4223 | 0.3407 | 0.0132 |
| SK-BR-3 | AZD8330 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 3257 | 4223 | 0.7712 | 0.6576 |
| SK-BR-3 | Barasertib | 0.12 | uM | LJP5 | 72 | hr | 1401 | 1398 | 4223 | 0.3310 | -0.0012 |