LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Canertinib | 10.0 | uM | LJP6 | 72 | hr | 1209 | 693 | 4093 | 0.1693 | -0.1792 |
| MCF7 | Celastrol | 10.0 | uM | LJP6 | 72 | hr | 1209 | 525 | 4093 | 0.1284 | -0.2373 |
| MCF7 | CGP60474 | 10.0 | uM | LJP5 | 72 | hr | 1209 | 568 | 4093 | 0.1389 | -0.2224 |
| MCF7 | CGP60474 | 10.0 | uM | LJP6 | 72 | hr | 1209 | 474 | 4093 | 0.1160 | -0.2549 |
| MCF7 | CHIR-99021 | 10.0 | uM | LJP6 | 72 | hr | 1209 | 1880 | 4093 | 0.4593 | 0.2325 |
| MCF7 | CP724714 | 10.0 | uM | LJP5 | 72 | hr | 1209 | 2778 | 4093 | 0.6787 | 0.5440 |
| MCF7 | CP466722 | 10.0 | uM | LJP5 | 72 | hr | 1209 | 1742 | 4093 | 0.4258 | 0.1849 |
| MCF7 | Crizotinib | 10.0 | uM | LJP5 | 72 | hr | 1209 | 886 | 4093 | 0.2166 | -0.1121 |
| MCF7 | Momelotinib | 10.0 | uM | LJP5 | 72 | hr | 1209 | 1263 | 4093 | 0.3087 | 0.0188 |
| MCF7 | Dasatinib | 10.0 | uM | LJP5 | 72 | hr | 1209 | 1660 | 4093 | 0.4057 | 0.1563 |
| MCF7 | Dasatinib | 10.0 | uM | LJP6 | 72 | hr | 1209 | 1231 | 4093 | 0.3008 | 0.0076 |
| MCF7 | Dovitinib | 10.0 | uM | LJP5 | 72 | hr | 1209 | 1654 | 4093 | 0.4041 | 0.1541 |
| MCF7 | Enzastaurin | 10.0 | uM | LJP5 | 72 | hr | 1209 | 2911 | 4093 | 0.7114 | 0.5903 |
| MCF7 | Erlotinib | 10.0 | uM | LJP5 | 72 | hr | 1209 | 3651 | 4093 | 0.8920 | 0.8467 |
| MCF7 | Foretinib | 10.0 | uM | LJP5 | 72 | hr | 1209 | 745 | 4093 | 0.1820 | -0.1611 |
| MCF7 | R406 | 10.0 | uM | LJP6 | 72 | hr | 1209 | 1925 | 4093 | 0.4705 | 0.2484 |
| MCF7 | Pictilisib | 10.0 | uM | LJP6 | 72 | hr | 1209 | 903 | 4093 | 0.2208 | -0.1061 |
| MCF7 | Gefitinib | 10.0 | uM | LJP6 | 72 | hr | 1209 | 3232 | 4093 | 0.7896 | 0.7014 |
| MCF7 | Geldanamycin | 10.0 | uM | LJP5 | 72 | hr | 1209 | 904 | 4093 | 0.2209 | -0.1060 |
| MCF7 | Geldanamycin | 10.0 | uM | LJP6 | 72 | hr | 1209 | 706 | 4093 | 0.1725 | -0.1746 |
| MCF7 | GSK1059615 | 10.0 | uM | LJP5 | 72 | hr | 1209 | 664 | 4093 | 0.1623 | -0.1891 |
| MCF7 | GSK1059615 | 10.0 | uM | LJP6 | 72 | hr | 1209 | 793 | 4093 | 0.1939 | -0.1442 |
| MCF7 | GSK1904529A | 10.0 | uM | LJP6 | 72 | hr | 1209 | 1997 | 4093 | 0.4881 | 0.2733 |
| MCF7 | Omipalisib | 10.0 | uM | LJP6 | 72 | hr | 1209 | 903 | 4093 | 0.2208 | -0.1061 |
| MCF7 | GSK 690693 | 10.0 | uM | LJP5 | 72 | hr | 1209 | 1699 | 4093 | 0.4152 | 0.1699 |