LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 BI-2536
0.37
uM
LJP6
72
hr
1311 1219 5013 0.2432 -0.0250
MDA-MB-231 BMS345541
0.37
uM
LJP6
72
hr
1311 4568 5013 0.9112 0.8797
MDA-MB-231 SNS-032
0.37
uM
LJP6
72
hr
1311 723 5013 0.1443 -0.1589
MDA-MB-231 GDC-0980
0.37
uM
LJP5
72
hr
1311 2963 5013 0.5910 0.4461
MDA-MB-231 NVP-AEW541
0.37
uM
LJP5
72
hr
1311 4797 5013 0.9569 0.9417
MDA-MB-231 SB590885
0.37
uM
LJP5
72
hr
1311 4944 5013 0.9863 0.9814
MDA-MB-231 PIK-93
0.37
uM
LJP5
72
hr
1311 5165 5013 1.0303 1.0410
MDA-MB-231 KIN001-043
0.37
uM
LJP6
72
hr
1311 4143 5013 0.8264 0.7649
MDA-MB-231 Alpelisib
0.37
uM
LJP5
72
hr
1311 4992 5013 0.9957 0.9942
MDA-MB-231 Luminespib
0.37
uM
LJP5
72
hr
1311 1023 5013 0.2041 -0.0779
MDA-MB-231 A443654
0.37
uM
LJP6
72
hr
1311 1805 5013 0.3600 0.1333
MDA-MB-231 OSI-027
0.37
uM
LJP6
72
hr
1311 4085 5013 0.8149 0.7493
MDA-MB-231 XMD11-85h
0.37
uM
LJP6
72
hr
1311 4551 5013 0.9077 0.8751
MDA-MB-231 HG-6-64-01
0.37
uM
LJP6
72
hr
1311 4134 5013 0.8246 0.7625
MDA-MB-231 WH-4-025
0.37
uM
LJP5
72
hr
1311 2774 5013 0.5533 0.3950
MDA-MB-231 WZ-4-145
0.37
uM
LJP6
72
hr
1311 4472 5013 0.8921 0.8538
MDA-MB-231 XMD16-144
0.37
uM
LJP5
72
hr
1311 1665 5013 0.3321 0.0954
MDA-MB-231 Brivanib
0.37
uM
LJP5
72
hr
1311 4983 5013 0.9940 0.9918
MDA-MB-231 Buparlisib
0.37
uM
LJP5
72
hr
1311 4524 5013 0.9024 0.8678
MDA-MB-231 BX-912
0.37
uM
LJP5
72
hr
1311 4567 5013 0.9111 0.8796
MDA-MB-231 Canertinib
0.37
uM
LJP6
72
hr
1311 4643 5013 0.9262 0.9000
MDA-MB-231 Celastrol
0.37
uM
LJP6
72
hr
1311 4281 5013 0.8540 0.8023
MDA-MB-231 CGP60474
0.37
uM
LJP5
72
hr
1311 830 5013 0.1657 -0.1300
MDA-MB-231 CGP60474
0.37
uM
LJP6
72
hr
1311 812 5013 0.1620 -0.1350
MDA-MB-231 CHIR-99021
0.37
uM
LJP6
72
hr
1311 4269 5013 0.8516 0.7990