LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|
MDA-MB-231 | BI-2536 | 0.37 | uM | LJP6 | 72 | hr | 1311 | 1219 | 5013 | 0.2432 | -0.0250 |
MDA-MB-231 | BMS345541 | 0.37 | uM | LJP6 | 72 | hr | 1311 | 4568 | 5013 | 0.9112 | 0.8797 |
MDA-MB-231 | SNS-032 | 0.37 | uM | LJP6 | 72 | hr | 1311 | 723 | 5013 | 0.1443 | -0.1589 |
MDA-MB-231 | GDC-0980 | 0.37 | uM | LJP5 | 72 | hr | 1311 | 2963 | 5013 | 0.5910 | 0.4461 |
MDA-MB-231 | NVP-AEW541 | 0.37 | uM | LJP5 | 72 | hr | 1311 | 4797 | 5013 | 0.9569 | 0.9417 |
MDA-MB-231 | SB590885 | 0.37 | uM | LJP5 | 72 | hr | 1311 | 4944 | 5013 | 0.9863 | 0.9814 |
MDA-MB-231 | PIK-93 | 0.37 | uM | LJP5 | 72 | hr | 1311 | 5165 | 5013 | 1.0303 | 1.0410 |
MDA-MB-231 | KIN001-043 | 0.37 | uM | LJP6 | 72 | hr | 1311 | 4143 | 5013 | 0.8264 | 0.7649 |
MDA-MB-231 | Alpelisib | 0.37 | uM | LJP5 | 72 | hr | 1311 | 4992 | 5013 | 0.9957 | 0.9942 |
MDA-MB-231 | Luminespib | 0.37 | uM | LJP5 | 72 | hr | 1311 | 1023 | 5013 | 0.2041 | -0.0779 |
MDA-MB-231 | A443654 | 0.37 | uM | LJP6 | 72 | hr | 1311 | 1805 | 5013 | 0.3600 | 0.1333 |
MDA-MB-231 | OSI-027 | 0.37 | uM | LJP6 | 72 | hr | 1311 | 4085 | 5013 | 0.8149 | 0.7493 |
MDA-MB-231 | XMD11-85h | 0.37 | uM | LJP6 | 72 | hr | 1311 | 4551 | 5013 | 0.9077 | 0.8751 |
MDA-MB-231 | HG-6-64-01 | 0.37 | uM | LJP6 | 72 | hr | 1311 | 4134 | 5013 | 0.8246 | 0.7625 |
MDA-MB-231 | WH-4-025 | 0.37 | uM | LJP5 | 72 | hr | 1311 | 2774 | 5013 | 0.5533 | 0.3950 |
MDA-MB-231 | WZ-4-145 | 0.37 | uM | LJP6 | 72 | hr | 1311 | 4472 | 5013 | 0.8921 | 0.8538 |
MDA-MB-231 | XMD16-144 | 0.37 | uM | LJP5 | 72 | hr | 1311 | 1665 | 5013 | 0.3321 | 0.0954 |
MDA-MB-231 | Brivanib | 0.37 | uM | LJP5 | 72 | hr | 1311 | 4983 | 5013 | 0.9940 | 0.9918 |
MDA-MB-231 | Buparlisib | 0.37 | uM | LJP5 | 72 | hr | 1311 | 4524 | 5013 | 0.9024 | 0.8678 |
MDA-MB-231 | BX-912 | 0.37 | uM | LJP5 | 72 | hr | 1311 | 4567 | 5013 | 0.9111 | 0.8796 |
MDA-MB-231 | Canertinib | 0.37 | uM | LJP6 | 72 | hr | 1311 | 4643 | 5013 | 0.9262 | 0.9000 |
MDA-MB-231 | Celastrol | 0.37 | uM | LJP6 | 72 | hr | 1311 | 4281 | 5013 | 0.8540 | 0.8023 |
MDA-MB-231 | CGP60474 | 0.37 | uM | LJP5 | 72 | hr | 1311 | 830 | 5013 | 0.1657 | -0.1300 |
MDA-MB-231 | CGP60474 | 0.37 | uM | LJP6 | 72 | hr | 1311 | 812 | 5013 | 0.1620 | -0.1350 |
MDA-MB-231 | CHIR-99021 | 0.37 | uM | LJP6 | 72 | hr | 1311 | 4269 | 5013 | 0.8516 | 0.7990 |