LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF7 TWS119
10.0
uM
LJP5
 72
hr
 1389 909 5667 0.1604 -0.1122
MCF7 Vemurafenib
10.0
uM
LJP5
 72
hr
 1389 5618 5667 0.9913 0.9885
MCF7 Withaferin A
10.0
uM
LJP5
 72
hr
 1389 1192 5667 0.2103 -0.0461
MCF7 Withaferin A
10.0
uM
LJP6
 72
hr
 1389 1181 5667 0.2084 -0.0486
MCF7 WYE-125132
10.0
uM
LJP6
 72
hr
 1389 1652 5667 0.2915 0.0615
MCF7 WZ3105
10.0
uM
LJP5
 72
hr
 1389 562 5667 0.0992 -0.1932
MCF7 XMD11-50
10.0
uM
LJP6
 72
hr
 1389 1481 5667 0.2614 0.0216
MCF7 Y39983
10.0
uM
LJP6
 72
hr
 1389 1162 5667 0.2050 -0.0531
MCF7 YM 201636
10.0
uM
LJP5
 72
hr
 1389 1595 5667 0.2814 0.0481
MCF7 ZSTK474
10.0
uM
LJP6
 72
hr
 1389 1515 5667 0.2674 0.0295
MDA-MB-231 Afatinib
0.04
uM
LJP6
 72
hr
 1311 4376 5013 0.8728 0.8278
MDA-MB-231 Sigma A6730
0.04
uM
LJP5
 72
hr
 1311 4443 5013 0.8863 0.8460
MDA-MB-231 Alvocidib
0.04
uM
LJP6
 72
hr
 1311 2608 5013 0.5203 0.3504
MDA-MB-231 AT-7519
0.04
uM
LJP6
 72
hr
 1311 3987 5013 0.7953 0.7227
MDA-MB-231 AZD 5438
0.04
uM
LJP6
 72
hr
 1311 4293 5013 0.8564 0.8055
MDA-MB-231 AZD-6482
0.04
uM
LJP5
 72
hr
 1311 4816 5013 0.9607 0.9467
MDA-MB-231 AZD7762
0.04
uM
LJP6
 72
hr
 1311 4468 5013 0.8912 0.8526
MDA-MB-231 AZD8055
0.04
uM
LJP6
 72
hr
 1311 2919 5013 0.5823 0.4343
MDA-MB-231 AZD8330
0.04
uM
LJP5
 72
hr
 1311 1710 5013 0.3411 0.1077
MDA-MB-231 Barasertib
0.04
uM
LJP5
 72
hr
 1311 1941 5013 0.3873 0.1702
MDA-MB-231 BI-2536
0.04
uM
LJP6
 72
hr
 1311 1312 5013 0.2617 0.0001
MDA-MB-231 BMS345541
0.04
uM
LJP6
 72
hr
 1311 4915 5013 0.9804 0.9734
MDA-MB-231 SNS-032
0.04
uM
LJP6
 72
hr
 1311 2350 5013 0.4687 0.2805
MDA-MB-231 GDC-0980
0.04
uM
LJP5
 72
hr
 1311 4041 5013 0.8060 0.7373
MDA-MB-231 NVP-AEW541
0.04
uM
LJP5
 72
hr
 1311 4908 5013 0.9790 0.9715