LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | PF431396 | 10.0 | uM | LJP5 | 72 | hr | 1389 | 665 | 5667 | 0.1173 | -0.1692 |
| MCF7 | PF477736 | 10.0 | uM | LJP5 | 72 | hr | 1389 | 1495 | 5667 | 0.2639 | 0.0249 |
| MCF7 | PF562271 | 10.0 | uM | LJP6 | 72 | hr | 1389 | 532 | 5667 | 0.0939 | -0.2003 |
| MCF7 | PHA-665752 | 10.0 | uM | LJP5 | 72 | hr | 1389 | 4976 | 5667 | 0.8779 | 0.8383 |
| MCF7 | PHA-793887 | 10.0 | uM | LJP6 | 72 | hr | 1389 | 578 | 5667 | 0.1020 | -0.1895 |
| MCF7 | PI103 | 10.0 | uM | LJP6 | 72 | hr | 1389 | 1130 | 5667 | 0.1995 | -0.0604 |
| MCF7 | PLX-4720 | 10.0 | uM | LJP5 | 72 | hr | 1389 | 3091 | 5667 | 0.5454 | 0.3979 |
| MCF7 | QL-X-138 | 10.0 | uM | LJP6 | 72 | hr | 1389 | 1134 | 5667 | 0.2002 | -0.0595 |
| MCF7 | QL-XII-47 | 10.0 | uM | LJP6 | 72 | hr | 1389 | 1074 | 5667 | 0.1896 | -0.0735 |
| MCF7 | Radicicol | 10.0 | uM | LJP5 | 72 | hr | 1389 | 1296 | 5667 | 0.2287 | -0.0217 |
| MCF7 | Radicicol | 10.0 | uM | LJP6 | 72 | hr | 1389 | 1223 | 5667 | 0.2158 | -0.0388 |
| MCF7 | Seliciclib | 10.0 | uM | LJP5 | 72 | hr | 1389 | 1278 | 5667 | 0.2255 | -0.0260 |
| MCF7 | Ruxolitinib | 10.0 | uM | LJP5 | 72 | hr | 1389 | 4975 | 5667 | 0.8778 | 0.8382 |
| MCF7 | XL147 | 10.0 | uM | LJP5 | 72 | hr | 1389 | 3984 | 5667 | 0.7030 | 0.6066 |
| MCF7 | Saracatinib | 10.0 | uM | LJP6 | 72 | hr | 1389 | 1667 | 5667 | 0.2942 | 0.0650 |
| MCF7 | Selumetinib | 10.0 | uM | LJP6 | 72 | hr | 1389 | 3071 | 5667 | 0.5419 | 0.3932 |
| MCF7 | Sirolimus | 10.0 | uM | LJP6 | 72 | hr | 1389 | 2978 | 5667 | 0.5255 | 0.3714 |
| MCF7 | Sorafenib | 10.0 | uM | LJP6 | 72 | hr | 1389 | 1891 | 5667 | 0.3338 | 0.1175 |
| MCF7 | SU11274 | 10.0 | uM | LJP5 | 72 | hr | 1389 | 1689 | 5667 | 0.2981 | 0.0702 |
| MCF7 | Fedratinib | 10.0 | uM | LJP5 | 72 | hr | 1389 | 862 | 5667 | 0.1521 | -0.1232 |
| MCF7 | TGX221 | 10.0 | uM | LJP5 | 72 | hr | 1389 | 5124 | 5667 | 0.9040 | 0.8729 |
| MCF7 | Torin1 | 10.0 | uM | LJP6 | 72 | hr | 1389 | 1257 | 5667 | 0.2218 | -0.0309 |
| MCF7 | Torin2 | 10.0 | uM | LJP5 | 72 | hr | 1389 | 1122 | 5667 | 0.1980 | -0.0624 |
| MCF7 | Tozasertib | 10.0 | uM | LJP5 | 72 | hr | 1389 | 1536 | 5667 | 0.2711 | 0.0345 |
| MCF7 | Trametinib | 10.0 | uM | LJP5 | 72 | hr | 1389 | 2877 | 5667 | 0.5076 | 0.3477 |