LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | JW-7-24-1 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 2439 | 5667 | 0.4304 | 0.2455 |
| MCF7 | Lapatinib | 1.11 | uM | LJP6 | 72 | hr | 1389 | 5610 | 5667 | 0.9899 | 0.9866 |
| MCF7 | LDN-193189 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 5282 | 5667 | 0.9320 | 0.9099 |
| MCF7 | Linifanib | 1.11 | uM | LJP6 | 72 | hr | 1389 | 4951 | 5667 | 0.8736 | 0.8325 |
| MCF7 | Linsitinib | 1.11 | uM | LJP5 | 72 | hr | 1389 | 3747 | 5667 | 0.6611 | 0.5511 |
| MCF7 | Mitoxantrone | 1.11 | uM | LJP5 | 72 | hr | 1389 | 1374 | 5667 | 0.2425 | -0.0034 |
| MCF7 | Mitoxantrone | 1.11 | uM | LJP6 | 72 | hr | 1389 | 1149 | 5667 | 0.2028 | -0.0560 |
| MCF7 | MK2206 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 2765 | 5667 | 0.4879 | 0.3217 |
| MCF7 | Neratinib | 1.11 | uM | LJP5 | 72 | hr | 1389 | 3862 | 5667 | 0.6814 | 0.5779 |
| MCF7 | Nilotinib | 1.11 | uM | LJP5 | 72 | hr | 1389 | 5707 | 5667 | 1.0070 | 1.0093 |
| MCF7 | Nintedanib | 1.11 | uM | LJP6 | 72 | hr | 1389 | 3670 | 5667 | 0.6475 | 0.5331 |
| MCF7 | NU7441 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 5906 | 5667 | 1.0421 | 1.0558 |
| MCF7 | Dactolisib | 1.11 | uM | LJP5 | 72 | hr | 1389 | 1784 | 5667 | 0.3148 | 0.0923 |
| MCF7 | NVP-TAE684 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 1198 | 5667 | 0.2114 | -0.0446 |
| MCF7 | Palbociclib | 1.11 | uM | LJP6 | 72 | hr | 1389 | 3058 | 5667 | 0.5397 | 0.3902 |
| MCF7 | PD0325901 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 3226 | 5667 | 0.5692 | 0.4293 |
| MCF7 | PD0325901 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 2953 | 5667 | 0.5211 | 0.3657 |
| MCF7 | PD173074 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 5752 | 5667 | 1.0150 | 1.0198 |
| MCF7 | PD184352 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 3827 | 5667 | 0.6752 | 0.5698 |
| MCF7 | Pelitinib | 1.11 | uM | LJP5 | 72 | hr | 1389 | 4980 | 5667 | 0.8787 | 0.8394 |
| MCF7 | PF431396 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 1589 | 5667 | 0.2804 | 0.0468 |
| MCF7 | PF477736 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 2299 | 5667 | 0.4056 | 0.2127 |
| MCF7 | PF562271 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 2503 | 5667 | 0.4417 | 0.2604 |
| MCF7 | PHA-665752 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 6391 | 5667 | 1.1277 | 1.1691 |
| MCF7 | PHA-793887 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 1507 | 5667 | 0.2659 | 0.0276 |