LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | CP724714 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 4672 | 5667 | 0.8244 | 0.7674 |
| MCF7 | CP466722 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 5956 | 5667 | 1.0509 | 1.0674 |
| MCF7 | Crizotinib | 1.11 | uM | LJP5 | 72 | hr | 1389 | 3285 | 5667 | 0.5796 | 0.4431 |
| MCF7 | Momelotinib | 1.11 | uM | LJP5 | 72 | hr | 1389 | 4328 | 5667 | 0.7636 | 0.6869 |
| MCF7 | Dasatinib | 1.11 | uM | LJP5 | 72 | hr | 1389 | 937 | 5667 | 0.1654 | -0.1055 |
| MCF7 | Dasatinib | 1.11 | uM | LJP6 | 72 | hr | 1389 | 1026 | 5667 | 0.1811 | -0.0848 |
| MCF7 | Dovitinib | 1.11 | uM | LJP5 | 72 | hr | 1389 | 4322 | 5667 | 0.7625 | 0.6855 |
| MCF7 | Enzastaurin | 1.11 | uM | LJP5 | 72 | hr | 1389 | 5842 | 5667 | 1.0308 | 1.0408 |
| MCF7 | Erlotinib | 1.11 | uM | LJP5 | 72 | hr | 1389 | 6611 | 5667 | 1.1664 | 1.2204 |
| MCF7 | Foretinib | 1.11 | uM | LJP5 | 72 | hr | 1389 | 1405 | 5667 | 0.2480 | 0.0038 |
| MCF7 | R406 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 4320 | 5667 | 0.7622 | 0.6851 |
| MCF7 | Pictilisib | 1.11 | uM | LJP6 | 72 | hr | 1389 | 1383 | 5667 | 0.2440 | -0.0014 |
| MCF7 | Gefitinib | 1.11 | uM | LJP6 | 72 | hr | 1389 | 5302 | 5667 | 0.9354 | 0.9145 |
| MCF7 | Geldanamycin | 1.11 | uM | LJP5 | 72 | hr | 1389 | 1638 | 5667 | 0.2891 | 0.0583 |
| MCF7 | Geldanamycin | 1.11 | uM | LJP6 | 72 | hr | 1389 | 1577 | 5667 | 0.2784 | 0.0441 |
| MCF7 | GSK1059615 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 2462 | 5667 | 0.4345 | 0.2509 |
| MCF7 | GSK1059615 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 2286 | 5667 | 0.4034 | 0.2098 |
| MCF7 | GSK1904529A | 1.11 | uM | LJP6 | 72 | hr | 1389 | 2878 | 5667 | 0.5079 | 0.3481 |
| MCF7 | Omipalisib | 1.11 | uM | LJP6 | 72 | hr | 1389 | 1179 | 5667 | 0.2081 | -0.0490 |
| MCF7 | GSK 690693 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 3147 | 5667 | 0.5552 | 0.4108 |
| MCF7 | GW843682X | 1.11 | uM | LJP6 | 72 | hr | 1389 | 1547 | 5667 | 0.2729 | 0.0369 |
| MCF7 | HG-5-113-01 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 2373 | 5667 | 0.4187 | 0.2300 |
| MCF7 | HG-5-88-01 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 2672 | 5667 | 0.4715 | 0.3000 |
| MCF7 | Imatinib | 1.11 | uM | LJP6 | 72 | hr | 1389 | 5907 | 5667 | 1.0422 | 1.0560 |
| MCF7 | JNK-9L | 1.11 | uM | LJP6 | 72 | hr | 1389 | 1329 | 5667 | 0.2345 | -0.0140 |