LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | BI-2536 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 1412 | 5667 | 0.2492 | 0.0055 |
| MCF7 | BMS345541 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 3666 | 5667 | 0.6469 | 0.5323 |
| MCF7 | SNS-032 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 595 | 5667 | 0.1051 | -0.1854 |
| MCF7 | GDC-0980 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 1235 | 5667 | 0.2180 | -0.0359 |
| MCF7 | NVP-AEW541 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 3110 | 5667 | 0.5487 | 0.4022 |
| MCF7 | SB590885 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 6309 | 5667 | 1.1131 | 1.1498 |
| MCF7 | PIK-93 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 5797 | 5667 | 1.0229 | 1.0303 |
| MCF7 | KIN001-043 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 4648 | 5667 | 0.8201 | 0.7617 |
| MCF7 | Alpelisib | 1.11 | uM | LJP5 | 72 | hr | 1389 | 3048 | 5667 | 0.5379 | 0.3878 |
| MCF7 | Luminespib | 1.11 | uM | LJP5 | 72 | hr | 1389 | 1301 | 5667 | 0.2296 | -0.0205 |
| MCF7 | A443654 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 804 | 5667 | 0.1419 | -0.1367 |
| MCF7 | OSI-027 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 2175 | 5667 | 0.3837 | 0.1837 |
| MCF7 | XMD11-85h | 1.11 | uM | LJP6 | 72 | hr | 1389 | 4435 | 5667 | 0.7826 | 0.7120 |
| MCF7 | HG-6-64-01 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 5483 | 5667 | 0.9674 | 0.9568 |
| MCF7 | WH-4-025 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 1603 | 5667 | 0.2829 | 0.0501 |
| MCF7 | WZ-4-145 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 2885 | 5667 | 0.5091 | 0.3497 |
| MCF7 | XMD16-144 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 1804 | 5667 | 0.3184 | 0.0971 |
| MCF7 | Brivanib | 1.11 | uM | LJP5 | 72 | hr | 1389 | 5582 | 5667 | 0.9848 | 0.9799 |
| MCF7 | Buparlisib | 1.11 | uM | LJP5 | 72 | hr | 1389 | 1167 | 5667 | 0.2060 | -0.0518 |
| MCF7 | BX-912 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 3569 | 5667 | 0.6298 | 0.5096 |
| MCF7 | Canertinib | 1.11 | uM | LJP6 | 72 | hr | 1389 | 3882 | 5667 | 0.6850 | 0.5828 |
| MCF7 | Celastrol | 1.11 | uM | LJP6 | 72 | hr | 1389 | 2084 | 5667 | 0.3677 | 0.1625 |
| MCF7 | CGP60474 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 397 | 5667 | 0.0701 | -0.2317 |
| MCF7 | CGP60474 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 581 | 5667 | 0.1025 | -0.1889 |
| MCF7 | CHIR-99021 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 3139 | 5667 | 0.5538 | 0.4090 |