LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF7 TWS119
0.04
uM
LJP5
 72
hr
 1389 6227 5667 1.0987 1.1308
MCF7 Vemurafenib
0.04
uM
LJP5
 72
hr
 1389 5823 5667 1.0274 1.0362
MCF7 Withaferin A
0.04
uM
LJP5
 72
hr
 1389 5874 5667 1.0364 1.0483
MCF7 Withaferin A
0.04
uM
LJP6
 72
hr
 1389 5669 5667 1.0002 1.0003
MCF7 WYE-125132
0.04
uM
LJP6
 72
hr
 1389 1958 5667 0.3456 0.1331
MCF7 WZ3105
0.04
uM
LJP5
 72
hr
 1389 544 5667 0.0960 -0.1975
MCF7 XMD11-50
0.04
uM
LJP6
 72
hr
 1389 4718 5667 0.8324 0.7780
MCF7 Y39983
0.04
uM
LJP6
 72
hr
 1389 5536 5667 0.9768 0.9693
MCF7 YM 201636
0.04
uM
LJP5
 72
hr
 1389 6388 5667 1.1270 1.1683
MCF7 ZSTK474
0.04
uM
LJP6
 72
hr
 1389 4300 5667 0.7588 0.6805
MCF7 Afatinib
0.12
uM
LJP6
 72
hr
 1389 4829 5667 0.8521 0.8041
MCF7 Sigma A6730
0.12
uM
LJP5
 72
hr
 1389 4612 5667 0.8137 0.7532
MCF7 Alvocidib
0.12
uM
LJP6
 72
hr
 1389 565 5667 0.0998 -0.1924
MCF7 AT-7519
0.12
uM
LJP6
 72
hr
 1389 2530 5667 0.4465 0.2668
MCF7 AZD 5438
0.12
uM
LJP6
 72
hr
 1389 3018 5667 0.5325 0.3807
MCF7 AZD-6482
0.12
uM
LJP5
 72
hr
 1389 6014 5667 1.0611 1.0810
MCF7 AZD7762
0.12
uM
LJP6
 72
hr
 1389 1691 5667 0.2984 0.0706
MCF7 AZD8055
0.12
uM
LJP6
 72
hr
 1389 1399 5667 0.2469 0.0024
MCF7 AZD8330
0.12
uM
LJP5
 72
hr
 1389 2430 5667 0.4288 0.2434
MCF7 Barasertib
0.12
uM
LJP5
 72
hr
 1389 1796 5667 0.3170 0.0952
MCF7 BI-2536
0.12
uM
LJP6
 72
hr
 1389 1510 5667 0.2664 0.0283
MCF7 BMS345541
0.12
uM
LJP6
 72
hr
 1389 5186 5667 0.9150 0.8875
MCF7 SNS-032
0.12
uM
LJP6
 72
hr
 1389 679 5667 0.1199 -0.1659
MCF7 GDC-0980
0.12
uM
LJP5
 72
hr
 1389 1457 5667 0.2572 0.0160
MCF7 NVP-AEW541
0.12
uM
LJP5
 72
hr
 1389 5446 5667 0.9609 0.9483