LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF7 PF431396
0.04
uM
LJP5
 72
hr
 1389 4828 5667 0.8519 0.8038
MCF7 PF477736
0.04
uM
LJP5
 72
hr
 1389 3686 5667 0.6503 0.5368
MCF7 PF562271
0.04
uM
LJP6
 72
hr
 1389 4722 5667 0.8332 0.7790
MCF7 PHA-665752
0.04
uM
LJP5
 72
hr
 1389 6381 5667 1.1258 1.1667
MCF7 PHA-793887
0.04
uM
LJP6
 72
hr
 1389 2290 5667 0.4041 0.2106
MCF7 PI103
0.04
uM
LJP6
 72
hr
 1389 4179 5667 0.7374 0.6522
MCF7 PLX-4720
0.04
uM
LJP5
 72
hr
 1389 6242 5667 1.1014 1.1343
MCF7 QL-X-138
0.04
uM
LJP6
 72
hr
 1389 3387 5667 0.5976 0.4670
MCF7 QL-XII-47
0.04
uM
LJP6
 72
hr
 1389 4059 5667 0.7163 0.6241
MCF7 Radicicol
0.04
uM
LJP5
 72
hr
 1389 3973 5667 0.7011 0.6040
MCF7 Radicicol
0.04
uM
LJP6
 72
hr
 1389 3671 5667 0.6477 0.5333
MCF7 Seliciclib
0.04
uM
LJP5
 72
hr
 1389 5996 5667 1.0579 1.0767
MCF7 Ruxolitinib
0.04
uM
LJP5
 72
hr
 1389 5760 5667 1.0163 1.0216
MCF7 XL147
0.04
uM
LJP5
 72
hr
 1389 6668 5667 1.1764 1.2337
MCF7 Saracatinib
0.04
uM
LJP6
 72
hr
 1389 4594 5667 0.8106 0.7491
MCF7 Selumetinib
0.04
uM
LJP6
 72
hr
 1389 4868 5667 0.8590 0.8132
MCF7 Sirolimus
0.04
uM
LJP6
 72
hr
 1389 3193 5667 0.5635 0.4218
MCF7 Sorafenib
0.04
uM
LJP6
 72
hr
 1389 5186 5667 0.9150 0.8874
MCF7 SU11274
0.04
uM
LJP5
 72
hr
 1389 6419 5667 1.1325 1.1755
MCF7 Fedratinib
0.04
uM
LJP5
 72
hr
 1389 6059 5667 1.0690 1.0914
MCF7 TGX221
0.04
uM
LJP5
 72
hr
 1389 4677 5667 0.8253 0.7685
MCF7 Torin1
0.04
uM
LJP6
 72
hr
 1389 1882 5667 0.3321 0.1153
MCF7 Torin2
0.04
uM
LJP5
 72
hr
 1389 1493 5667 0.2635 0.0244
MCF7 Tozasertib
0.04
uM
LJP5
 72
hr
 1389 1560 5667 0.2752 0.0399
MCF7 Trametinib
0.04
uM
LJP5
 72
hr
 1389 2684 5667 0.4736 0.3028