LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A JW-7-24-1
3.33
uM
LJP6
 72
hr
 1694 11504 11155 1.0313 1.0369
MCF 10A Lapatinib
3.33
uM
LJP6
 72
hr
 1694 8365 11155 0.7498 0.7051
MCF 10A LDN-193189
3.33
uM
LJP5
 72
hr
 1694 10406 11155 0.9329 0.9208
MCF 10A Linifanib
3.33
uM
LJP6
 72
hr
 1694 11019 11155 0.9878 0.9856
MCF 10A Linsitinib
3.33
uM
LJP5
 72
hr
 1694 7909 11155 0.7090 0.6569
MCF 10A Mitoxantrone
3.33
uM
LJP5
 72
hr
 1694 775 11155 0.0695 -0.0971
MCF 10A Mitoxantrone
3.33
uM
LJP6
 72
hr
 1694 630 11155 0.0565 -0.1125
MCF 10A MK2206
3.33
uM
LJP6
 72
hr
 1694 10046 11155 0.9006 0.8828
MCF 10A Neratinib
3.33
uM
LJP5
 72
hr
 1694 2674 11155 0.2398 0.1036
MCF 10A Nilotinib
3.33
uM
LJP5
 72
hr
 1694 11124 11155 0.9972 0.9967
MCF 10A Nintedanib
3.33
uM
LJP6
 72
hr
 1694 9454 11155 0.8475 0.8202
MCF 10A NU7441
3.33
uM
LJP5
 72
hr
 1694 10125 11155 0.9077 0.8911
MCF 10A Dactolisib
3.33
uM
LJP5
 72
hr
 1694 2934 11155 0.2630 0.1310
MCF 10A NVP-TAE684
3.33
uM
LJP6
 72
hr
 1694 4764 11155 0.4271 0.3245
MCF 10A Palbociclib
3.33
uM
LJP6
 72
hr
 1694 5616 11155 0.5035 0.4146
MCF 10A PD0325901
3.33
uM
LJP5
 72
hr
 1694 2566 11155 0.2301 0.0922
MCF 10A PD0325901
3.33
uM
LJP6
 72
hr
 1694 2257 11155 0.2024 0.0595
MCF 10A PD173074
3.33
uM
LJP6
 72
hr
 1694 10831 11155 0.9710 0.9658
MCF 10A PD184352
3.33
uM
LJP5
 72
hr
 1694 3347 11155 0.3000 0.1747
MCF 10A Pelitinib
3.33
uM
LJP5
 72
hr
 1694 2453 11155 0.2199 0.0802
MCF 10A PF431396
3.33
uM
LJP5
 72
hr
 1694 1880 11155 0.1685 0.0196
MCF 10A PF477736
3.33
uM
LJP5
 72
hr
 1694 4724 11155 0.4235 0.3202
MCF 10A PF562271
3.33
uM
LJP6
 72
hr
 1694 2166 11155 0.1942 0.0499
MCF 10A PHA-665752
3.33
uM
LJP5
 72
hr
 1694 10469 11155 0.9385 0.9275
MCF 10A PHA-793887
3.33
uM
LJP6
 72
hr
 1694 1580 11155 0.1416 -0.0121