LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A Dasatinib
0.37
uM
LJP6
72
hr
1694 2661 11155 0.2386 0.1022
MCF 10A Dovitinib
0.37
uM
LJP5
72
hr
1694 7094 11155 0.6360 0.5708
MCF 10A Enzastaurin
0.37
uM
LJP5
72
hr
1694 11178 11155 1.0020 1.0024
MCF 10A Erlotinib
0.37
uM
LJP5
72
hr
1694 6099 11155 0.5467 0.4656
MCF 10A Foretinib
0.37
uM
LJP5
72
hr
1694 10225 11155 0.9166 0.9017
MCF 10A R406
0.37
uM
LJP6
72
hr
1694 11086 11155 0.9938 0.9926
MCF 10A Pictilisib
0.37
uM
LJP6
72
hr
1694 7344 11155 0.6584 0.5972
MCF 10A Gefitinib
0.37
uM
LJP6
72
hr
1694 3801 11155 0.3407 0.2227
MCF 10A Geldanamycin
0.37
uM
LJP5
72
hr
1694 1363 11155 0.1222 -0.0350
MCF 10A Geldanamycin
0.37
uM
LJP6
72
hr
1694 1167 11155 0.1047 -0.0557
MCF 10A GSK1059615
0.37
uM
LJP5
72
hr
1694 7368 11155 0.6605 0.5997
MCF 10A GSK1059615
0.37
uM
LJP6
72
hr
1694 6672 11155 0.5981 0.5262
MCF 10A GSK1904529A
0.37
uM
LJP6
72
hr
1694 6649 11155 0.5961 0.5238
MCF 10A Omipalisib
0.37
uM
LJP6
72
hr
1694 1730 11155 0.1551 0.0038
MCF 10A GSK 690693
0.37
uM
LJP5
72
hr
1694 10752 11155 0.9638 0.9574
MCF 10A GW843682X
0.37
uM
LJP6
72
hr
1694 5668 11155 0.5081 0.4200
MCF 10A HG-5-113-01
0.37
uM
LJP5
72
hr
1694 8904 11155 0.7982 0.7620
MCF 10A HG-5-88-01
0.37
uM
LJP6
72
hr
1694 8518 11155 0.7636 0.7212
MCF 10A Imatinib
0.37
uM
LJP6
72
hr
1694 11114 11155 0.9963 0.9957
MCF 10A JNK-9L
0.37
uM
LJP6
72
hr
1694 9206 11155 0.8253 0.7940
MCF 10A JW-7-24-1
0.37
uM
LJP6
72
hr
1694 11550 11155 1.0354 1.0417
MCF 10A Lapatinib
0.37
uM
LJP6
72
hr
1694 10095 11155 0.9050 0.8879
MCF 10A LDN-193189
0.37
uM
LJP5
72
hr
1694 10795 11155 0.9677 0.9619
MCF 10A Linifanib
0.37
uM
LJP6
72
hr
1694 11418 11155 1.0236 1.0278
MCF 10A Linsitinib
0.37
uM
LJP5
72
hr
1694 9053 11155 0.8115 0.7778