LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | Dasatinib | 0.37 | uM | LJP6 | 72 | hr | 1694 | 2661 | 11155 | 0.2386 | 0.1022 |
MCF 10A | Dovitinib | 0.37 | uM | LJP5 | 72 | hr | 1694 | 7094 | 11155 | 0.6360 | 0.5708 |
MCF 10A | Enzastaurin | 0.37 | uM | LJP5 | 72 | hr | 1694 | 11178 | 11155 | 1.0020 | 1.0024 |
MCF 10A | Erlotinib | 0.37 | uM | LJP5 | 72 | hr | 1694 | 6099 | 11155 | 0.5467 | 0.4656 |
MCF 10A | Foretinib | 0.37 | uM | LJP5 | 72 | hr | 1694 | 10225 | 11155 | 0.9166 | 0.9017 |
MCF 10A | R406 | 0.37 | uM | LJP6 | 72 | hr | 1694 | 11086 | 11155 | 0.9938 | 0.9926 |
MCF 10A | Pictilisib | 0.37 | uM | LJP6 | 72 | hr | 1694 | 7344 | 11155 | 0.6584 | 0.5972 |
MCF 10A | Gefitinib | 0.37 | uM | LJP6 | 72 | hr | 1694 | 3801 | 11155 | 0.3407 | 0.2227 |
MCF 10A | Geldanamycin | 0.37 | uM | LJP5 | 72 | hr | 1694 | 1363 | 11155 | 0.1222 | -0.0350 |
MCF 10A | Geldanamycin | 0.37 | uM | LJP6 | 72 | hr | 1694 | 1167 | 11155 | 0.1047 | -0.0557 |
MCF 10A | GSK1059615 | 0.37 | uM | LJP5 | 72 | hr | 1694 | 7368 | 11155 | 0.6605 | 0.5997 |
MCF 10A | GSK1059615 | 0.37 | uM | LJP6 | 72 | hr | 1694 | 6672 | 11155 | 0.5981 | 0.5262 |
MCF 10A | GSK1904529A | 0.37 | uM | LJP6 | 72 | hr | 1694 | 6649 | 11155 | 0.5961 | 0.5238 |
MCF 10A | Omipalisib | 0.37 | uM | LJP6 | 72 | hr | 1694 | 1730 | 11155 | 0.1551 | 0.0038 |
MCF 10A | GSK 690693 | 0.37 | uM | LJP5 | 72 | hr | 1694 | 10752 | 11155 | 0.9638 | 0.9574 |
MCF 10A | GW843682X | 0.37 | uM | LJP6 | 72 | hr | 1694 | 5668 | 11155 | 0.5081 | 0.4200 |
MCF 10A | HG-5-113-01 | 0.37 | uM | LJP5 | 72 | hr | 1694 | 8904 | 11155 | 0.7982 | 0.7620 |
MCF 10A | HG-5-88-01 | 0.37 | uM | LJP6 | 72 | hr | 1694 | 8518 | 11155 | 0.7636 | 0.7212 |
MCF 10A | Imatinib | 0.37 | uM | LJP6 | 72 | hr | 1694 | 11114 | 11155 | 0.9963 | 0.9957 |
MCF 10A | JNK-9L | 0.37 | uM | LJP6 | 72 | hr | 1694 | 9206 | 11155 | 0.8253 | 0.7940 |
MCF 10A | JW-7-24-1 | 0.37 | uM | LJP6 | 72 | hr | 1694 | 11550 | 11155 | 1.0354 | 1.0417 |
MCF 10A | Lapatinib | 0.37 | uM | LJP6 | 72 | hr | 1694 | 10095 | 11155 | 0.9050 | 0.8879 |
MCF 10A | LDN-193189 | 0.37 | uM | LJP5 | 72 | hr | 1694 | 10795 | 11155 | 0.9677 | 0.9619 |
MCF 10A | Linifanib | 0.37 | uM | LJP6 | 72 | hr | 1694 | 11418 | 11155 | 1.0236 | 1.0278 |
MCF 10A | Linsitinib | 0.37 | uM | LJP5 | 72 | hr | 1694 | 9053 | 11155 | 0.8115 | 0.7778 |