LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A SB590885
0.37
uM
LJP5
 72
hr
 1694 11288 11155 1.0119 1.0140
MCF 10A PIK-93
0.37
uM
LJP5
 72
hr
 1694 11351 11155 1.0175 1.0206
MCF 10A KIN001-043
0.37
uM
LJP6
 72
hr
 1694 10973 11155 0.9836 0.9807
MCF 10A Alpelisib
0.37
uM
LJP5
 72
hr
 1694 9524 11155 0.8537 0.8276
MCF 10A Luminespib
0.37
uM
LJP5
 72
hr
 1694 1259 11155 0.1129 -0.0459
MCF 10A A443654
0.37
uM
LJP6
 72
hr
 1694 3893 11155 0.3490 0.2324
MCF 10A OSI-027
0.37
uM
LJP6
 72
hr
 1694 6101 11155 0.5469 0.4658
MCF 10A XMD11-85h
0.37
uM
LJP6
 72
hr
 1694 11087 11155 0.9938 0.9927
MCF 10A HG-6-64-01
0.37
uM
LJP6
 72
hr
 1694 11323 11155 1.0150 1.0177
MCF 10A WH-4-025
0.37
uM
LJP5
 72
hr
 1694 9113 11155 0.8169 0.7841
MCF 10A WZ-4-145
0.37
uM
LJP6
 72
hr
 1694 10018 11155 0.8981 0.8798
MCF 10A XMD16-144
0.37
uM
LJP5
 72
hr
 1694 2195 11155 0.1968 0.0530
MCF 10A Brivanib
0.37
uM
LJP5
 72
hr
 1694 10776 11155 0.9660 0.9599
MCF 10A Buparlisib
0.37
uM
LJP5
 72
hr
 1694 9711 11155 0.8705 0.8473
MCF 10A BX-912
0.37
uM
LJP5
 72
hr
 1694 8956 11155 0.8028 0.7675
MCF 10A Canertinib
0.37
uM
LJP6
 72
hr
 1694 4255 11155 0.3815 0.2707
MCF 10A Celastrol
0.37
uM
LJP6
 72
hr
 1694 11629 11155 1.0425 1.0501
MCF 10A CGP60474
0.37
uM
LJP5
 72
hr
 1694 405 11155 0.0363 -0.1363
MCF 10A CGP60474
0.37
uM
LJP6
 72
hr
 1694 364 11155 0.0326 -0.1406
MCF 10A CHIR-99021
0.37
uM
LJP6
 72
hr
 1694 11724 11155 1.0509 1.0601
MCF 10A CP724714
0.37
uM
LJP5
 72
hr
 1694 10714 11155 0.9605 0.9534
MCF 10A CP466722
0.37
uM
LJP5
 72
hr
 1694 11256 11155 1.0090 1.0106
MCF 10A Crizotinib
0.37
uM
LJP5
 72
hr
 1694 9989 11155 0.8955 0.8768
MCF 10A Momelotinib
0.37
uM
LJP5
 72
hr
 1694 9410 11155 0.8436 0.8155
MCF 10A Dasatinib
0.37
uM
LJP5
 72
hr
 1694 3080 11155 0.2761 0.1465