LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A TWS119
0.12
uM
LJP5
 72
hr
 1694 11268 11155 1.0101 1.0119
MCF 10A Vemurafenib
0.12
uM
LJP5
 72
hr
 1694 10857 11155 0.9733 0.9685
MCF 10A Withaferin A
0.12
uM
LJP5
 72
hr
 1694 11017 11155 0.9876 0.9854
MCF 10A Withaferin A
0.12
uM
LJP6
 72
hr
 1694 10930 11155 0.9798 0.9762
MCF 10A WYE-125132
0.12
uM
LJP6
 72
hr
 1694 3859 11155 0.3459 0.2288
MCF 10A WZ3105
0.12
uM
LJP5
 72
hr
 1694 3693 11155 0.3311 0.2113
MCF 10A XMD11-50
0.12
uM
LJP6
 72
hr
 1694 10575 11155 0.9480 0.9387
MCF 10A Y39983
0.12
uM
LJP6
 72
hr
 1694 8937 11155 0.8011 0.7655
MCF 10A YM 201636
0.12
uM
LJP5
 72
hr
 1694 11015 11155 0.9874 0.9852
MCF 10A ZSTK474
0.12
uM
LJP6
 72
hr
 1694 9950 11155 0.8920 0.8726
MCF 10A Afatinib
0.37
uM
LJP6
 72
hr
 1694 1703 11155 0.1527 0.0009
MCF 10A Sigma A6730
0.37
uM
LJP5
 72
hr
 1694 10813 11155 0.9693 0.9638
MCF 10A Alvocidib
0.37
uM
LJP6
 72
hr
 1694 300 11155 0.0269 -0.1474
MCF 10A AT-7519
0.37
uM
LJP6
 72
hr
 1694 6457 11155 0.5789 0.5035
MCF 10A AZD 5438
0.37
uM
LJP6
 72
hr
 1694 6413 11155 0.5749 0.4988
MCF 10A AZD-6482
0.37
uM
LJP5
 72
hr
 1694 10494 11155 0.9408 0.9301
MCF 10A AZD7762
0.37
uM
LJP6
 72
hr
 1694 6905 11155 0.6190 0.5508
MCF 10A AZD8055
0.37
uM
LJP6
 72
hr
 1694 3172 11155 0.2844 0.1563
MCF 10A AZD8330
0.37
uM
LJP5
 72
hr
 1694 2519 11155 0.2258 0.0872
MCF 10A Barasertib
0.37
uM
LJP5
 72
hr
 1694 1965 11155 0.1762 0.0287
MCF 10A BI-2536
0.37
uM
LJP6
 72
hr
 1694 1182 11155 0.1060 -0.0541
MCF 10A BMS345541
0.37
uM
LJP6
 72
hr
 1694 10565 11155 0.9471 0.9376
MCF 10A SNS-032
0.37
uM
LJP6
 72
hr
 1694 464 11155 0.0416 -0.1300
MCF 10A GDC-0980
0.37
uM
LJP5
 72
hr
 1694 4209 11155 0.3774 0.2659
MCF 10A NVP-AEW541
0.37
uM
LJP5
 72
hr
 1694 10089 11155 0.9044 0.8873