LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | PI103 | 10.0 | uM | LJP6 | 72 | hr | 765 | 684 | 3124 | 0.2190 | -0.0342 |
| Hs 578T | PLX-4720 | 10.0 | uM | LJP5 | 72 | hr | 765 | 2248 | 3124 | 0.7195 | 0.6285 |
| Hs 578T | QL-X-138 | 10.0 | uM | LJP6 | 72 | hr | 765 | 572 | 3124 | 0.1832 | -0.0817 |
| Hs 578T | QL-XII-47 | 10.0 | uM | LJP6 | 72 | hr | 765 | 412 | 3124 | 0.1319 | -0.1496 |
| Hs 578T | Radicicol | 10.0 | uM | LJP5 | 72 | hr | 765 | 693 | 3124 | 0.2219 | -0.0304 |
| Hs 578T | Radicicol | 10.0 | uM | LJP6 | 72 | hr | 765 | 748 | 3124 | 0.2395 | -0.0071 |
| Hs 578T | Seliciclib | 10.0 | uM | LJP5 | 72 | hr | 765 | 2245 | 3124 | 0.7186 | 0.6274 |
| Hs 578T | Ruxolitinib | 10.0 | uM | LJP5 | 72 | hr | 765 | 2151 | 3124 | 0.6884 | 0.5874 |
| Hs 578T | XL147 | 10.0 | uM | LJP5 | 72 | hr | 765 | 2579 | 3124 | 0.8254 | 0.7688 |
| Hs 578T | Saracatinib | 10.0 | uM | LJP6 | 72 | hr | 765 | 1175 | 3124 | 0.3761 | 0.1738 |
| Hs 578T | Selumetinib | 10.0 | uM | LJP6 | 72 | hr | 765 | 1102 | 3124 | 0.3527 | 0.1428 |
| Hs 578T | Sirolimus | 10.0 | uM | LJP6 | 72 | hr | 765 | 1779 | 3124 | 0.5694 | 0.4297 |
| Hs 578T | Sorafenib | 10.0 | uM | LJP6 | 72 | hr | 765 | 2854 | 3124 | 0.9136 | 0.8856 |
| Hs 578T | SU11274 | 10.0 | uM | LJP5 | 72 | hr | 765 | 886 | 3124 | 0.2837 | 0.0514 |
| Hs 578T | Fedratinib | 10.0 | uM | LJP5 | 72 | hr | 765 | 321 | 3124 | 0.1028 | -0.1881 |
| Hs 578T | TGX221 | 10.0 | uM | LJP5 | 72 | hr | 765 | 2016 | 3124 | 0.6453 | 0.5303 |
| Hs 578T | Torin1 | 10.0 | uM | LJP6 | 72 | hr | 765 | 482 | 3124 | 0.1543 | -0.1200 |
| Hs 578T | Torin2 | 10.0 | uM | LJP5 | 72 | hr | 765 | 397 | 3124 | 0.1273 | -0.1557 |
| Hs 578T | Tozasertib | 10.0 | uM | LJP5 | 72 | hr | 765 | 711 | 3124 | 0.2277 | -0.0228 |
| Hs 578T | Trametinib | 10.0 | uM | LJP5 | 72 | hr | 765 | 1000 | 3124 | 0.3201 | 0.0996 |
| Hs 578T | TWS119 | 10.0 | uM | LJP5 | 72 | hr | 765 | 424 | 3124 | 0.1359 | -0.1443 |
| Hs 578T | Vemurafenib | 10.0 | uM | LJP5 | 72 | hr | 765 | 1944 | 3124 | 0.6224 | 0.5000 |
| Hs 578T | Withaferin A | 10.0 | uM | LJP5 | 72 | hr | 765 | 322 | 3124 | 0.1033 | -0.1875 |
| Hs 578T | Withaferin A | 10.0 | uM | LJP6 | 72 | hr | 765 | 326 | 3124 | 0.1043 | -0.1861 |
| Hs 578T | WYE-125132 | 10.0 | uM | LJP6 | 72 | hr | 765 | 658 | 3124 | 0.2108 | -0.0451 |