LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T Mitoxantrone
1.11
uM
LJP5
 72
hr
 765 448 3124 0.1435 -0.1342
Hs 578T Mitoxantrone
1.11
uM
LJP6
 72
hr
 765 434 3124 0.1389 -0.1403
Hs 578T MK2206
1.11
uM
LJP6
 72
hr
 765 2116 3124 0.6772 0.5726
Hs 578T Neratinib
1.11
uM
LJP5
 72
hr
 765 2244 3124 0.7184 0.6271
Hs 578T Nilotinib
1.11
uM
LJP5
 72
hr
 765 3401 3124 1.0886 1.1173
Hs 578T Nintedanib
1.11
uM
LJP6
 72
hr
 765 2180 3124 0.6978 0.5998
Hs 578T NU7441
1.11
uM
LJP5
 72
hr
 765 2462 3124 0.7881 0.7193
Hs 578T Dactolisib
1.11
uM
LJP5
 72
hr
 765 798 3124 0.2556 0.0142
Hs 578T NVP-TAE684
1.11
uM
LJP6
 72
hr
 765 1479 3124 0.4734 0.3026
Hs 578T Palbociclib
1.11
uM
LJP6
 72
hr
 765 1554 3124 0.4974 0.3344
Hs 578T PD0325901
1.11
uM
LJP5
 72
hr
 765 1144 3124 0.3662 0.1608
Hs 578T PD0325901
1.11
uM
LJP6
 72
hr
 765 1101 3124 0.3525 0.1425
Hs 578T PD173074
1.11
uM
LJP6
 72
hr
 765 2441 3124 0.7812 0.7103
Hs 578T PD184352
1.11
uM
LJP5
 72
hr
 765 1637 3124 0.5240 0.3697
Hs 578T Pelitinib
1.11
uM
LJP5
 72
hr
 765 2396 3124 0.7668 0.6912
Hs 578T PF431396
1.11
uM
LJP5
 72
hr
 765 1142 3124 0.3656 0.1599
Hs 578T PF477736
1.11
uM
LJP5
 72
hr
 765 522 3124 0.1671 -0.1030
Hs 578T PF562271
1.11
uM
LJP6
 72
hr
 765 1969 3124 0.6304 0.5105
Hs 578T PHA-665752
1.11
uM
LJP5
 72
hr
 765 3076 3124 0.9847 0.9797
Hs 578T PHA-793887
1.11
uM
LJP6
 72
hr
 765 790 3124 0.2529 0.0107
Hs 578T PI103
1.11
uM
LJP6
 72
hr
 765 768 3124 0.2460 0.0015
Hs 578T PLX-4720
1.11
uM
LJP5
 72
hr
 765 3735 3124 1.1955 1.2589
Hs 578T QL-X-138
1.11
uM
LJP6
 72
hr
 765 1711 3124 0.5478 0.4012
Hs 578T QL-XII-47
1.11
uM
LJP6
 72
hr
 765 2041 3124 0.6534 0.5411
Hs 578T Radicicol
1.11
uM
LJP5
 72
hr
 765 1495 3124 0.4787 0.3097