LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T Radicicol
1.11
uM
LJP6
 72
hr
 765 1414 3124 0.4527 0.2752
Hs 578T Seliciclib
1.11
uM
LJP5
 72
hr
 765 3091 3124 0.9895 0.9861
Hs 578T Ruxolitinib
1.11
uM
LJP5
 72
hr
 765 3003 3124 0.9613 0.9488
Hs 578T XL147
1.11
uM
LJP5
 72
hr
 765 3041 3124 0.9735 0.9649
Hs 578T Saracatinib
1.11
uM
LJP6
 72
hr
 765 2179 3124 0.6975 0.5994
Hs 578T Selumetinib
1.11
uM
LJP6
 72
hr
 765 1484 3124 0.4751 0.3049
Hs 578T Sirolimus
1.11
uM
LJP6
 72
hr
 765 1857 3124 0.5943 0.4628
Hs 578T Sorafenib
1.11
uM
LJP6
 72
hr
 765 3829 3124 1.2257 1.2988
Hs 578T SU11274
1.11
uM
LJP5
 72
hr
 765 2770 3124 0.8865 0.8497
Hs 578T Fedratinib
1.11
uM
LJP5
 72
hr
 765 2156 3124 0.6902 0.5898
Hs 578T TGX221
1.11
uM
LJP5
 72
hr
 765 2711 3124 0.8679 0.8250
Hs 578T Torin1
1.11
uM
LJP6
 72
hr
 765 781 3124 0.2501 0.0069
Hs 578T Torin2
1.11
uM
LJP5
 72
hr
 765 535 3124 0.1714 -0.0972
Hs 578T Tozasertib
1.11
uM
LJP5
 72
hr
 765 752 3124 0.2407 -0.0055
Hs 578T Trametinib
1.11
uM
LJP5
 72
hr
 765 975 3124 0.3121 0.0890
Hs 578T TWS119
1.11
uM
LJP5
 72
hr
 765 2794 3124 0.8943 0.8601
Hs 578T Vemurafenib
1.11
uM
LJP5
 72
hr
 765 3290 3124 1.0532 1.0704
Hs 578T Withaferin A
1.11
uM
LJP5
 72
hr
 765 554 3124 0.1775 -0.0892
Hs 578T Withaferin A
1.11
uM
LJP6
 72
hr
 765 501 3124 0.1605 -0.1118
Hs 578T WYE-125132
1.11
uM
LJP6
 72
hr
 765 871 3124 0.2790 0.0452
Hs 578T WZ3105
1.11
uM
LJP5
 72
hr
 765 412 3124 0.1320 -0.1495
Hs 578T XMD11-50
1.11
uM
LJP6
 72
hr
 765 2104 3124 0.6735 0.5676
Hs 578T Y39983
1.11
uM
LJP6
 72
hr
 765 2320 3124 0.7427 0.6593
Hs 578T YM 201636
1.11
uM
LJP5
 72
hr
 765 2705 3124 0.8659 0.8225
Hs 578T ZSTK474
1.11
uM
LJP6
 72
hr
 765 1316 3124 0.4212 0.2335