LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T Afatinib
3.33
uM
LJP6
 72
hr
 765 2529 3124 0.8095 0.7477
Hs 578T Sigma A6730
3.33
uM
LJP5
 72
hr
 765 2784 3124 0.8911 0.8558
Hs 578T Alvocidib
3.33
uM
LJP6
 72
hr
 765 369 3124 0.1183 -0.1676
Hs 578T AT-7519
3.33
uM
LJP6
 72
hr
 765 300 3124 0.0960 -0.1971
Hs 578T AZD 5438
3.33
uM
LJP6
 72
hr
 765 522 3124 0.1673 -0.1027
Hs 578T AZD-6482
3.33
uM
LJP5
 72
hr
 765 2022 3124 0.6474 0.5330
Hs 578T AZD7762
3.33
uM
LJP6
 72
hr
 765 466 3124 0.1493 -0.1266
Hs 578T AZD8055
3.33
uM
LJP6
 72
hr
 765 829 3124 0.2655 0.0274
Hs 578T AZD8330
3.33
uM
LJP5
 72
hr
 765 972 3124 0.3113 0.0880
Hs 578T Barasertib
3.33
uM
LJP5
 72
hr
 765 945 3124 0.3026 0.0764
Hs 578T BI-2536
3.33
uM
LJP6
 72
hr
 765 527 3124 0.1689 -0.1006
Hs 578T BMS345541
3.33
uM
LJP6
 72
hr
 765 2499 3124 0.8000 0.7352
Hs 578T SNS-032
3.33
uM
LJP6
 72
hr
 765 431 3124 0.1379 -0.1416
Hs 578T GDC-0980
3.33
uM
LJP5
 72
hr
 765 805 3124 0.2576 0.0169
Hs 578T NVP-AEW541
3.33
uM
LJP5
 72
hr
 765 3119 3124 0.9984 0.9979
Hs 578T SB590885
3.33
uM
LJP5
 72
hr
 765 3864 3124 1.2369 1.3137
Hs 578T PIK-93
3.33
uM
LJP5
 72
hr
 765 1521 3124 0.4868 0.3204
Hs 578T KIN001-043
3.33
uM
LJP6
 72
hr
 765 2411 3124 0.7719 0.6979
Hs 578T Alpelisib
3.33
uM
LJP5
 72
hr
 765 2409 3124 0.7710 0.6967
Hs 578T Luminespib
3.33
uM
LJP5
 72
hr
 765 649 3124 0.2077 -0.0492
Hs 578T A443654
3.33
uM
LJP6
 72
hr
 765 321 3124 0.1028 -0.1881
Hs 578T OSI-027
3.33
uM
LJP6
 72
hr
 765 1165 3124 0.3729 0.1695
Hs 578T XMD11-85h
3.33
uM
LJP6
 72
hr
 765 2622 3124 0.8394 0.7873
Hs 578T HG-6-64-01
3.33
uM
LJP6
 72
hr
 765 568 3124 0.1818 -0.0835
Hs 578T WH-4-025
3.33
uM
LJP5
 72
hr
 765 399 3124 0.1278 -0.1550