LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T R406
0.12
uM
LJP6
 72
hr
 765 2759 3124 0.8832 0.8454
Hs 578T Pictilisib
0.12
uM
LJP6
 72
hr
 765 2186 3124 0.6998 0.6025
Hs 578T Gefitinib
0.12
uM
LJP6
 72
hr
 765 3041 3124 0.9735 0.9649
Hs 578T Geldanamycin
0.12
uM
LJP5
 72
hr
 765 838 3124 0.2682 0.0309
Hs 578T Geldanamycin
0.12
uM
LJP6
 72
hr
 765 963 3124 0.3082 0.0839
Hs 578T GSK1059615
0.12
uM
LJP5
 72
hr
 765 2759 3124 0.8831 0.8452
Hs 578T GSK1059615
0.12
uM
LJP6
 72
hr
 765 2413 3124 0.7724 0.6986
Hs 578T GSK1904529A
0.12
uM
LJP6
 72
hr
 765 2929 3124 0.9376 0.9174
Hs 578T Omipalisib
0.12
uM
LJP6
 72
hr
 765 720 3124 0.2305 -0.0190
Hs 578T GSK 690693
0.12
uM
LJP5
 72
hr
 765 2482 3124 0.7946 0.7280
Hs 578T GW843682X
0.12
uM
LJP6
 72
hr
 765 2379 3124 0.7614 0.6840
Hs 578T HG-5-113-01
0.12
uM
LJP5
 72
hr
 765 2863 3124 0.9165 0.8894
Hs 578T HG-5-88-01
0.12
uM
LJP6
 72
hr
 765 3009 3124 0.9631 0.9512
Hs 578T Imatinib
0.12
uM
LJP6
 72
hr
 765 3128 3124 1.0011 1.0015
Hs 578T JNK-9L
0.12
uM
LJP6
 72
hr
 765 3104 3124 0.9935 0.9914
Hs 578T JW-7-24-1
0.12
uM
LJP6
 72
hr
 765 2846 3124 0.9110 0.8821
Hs 578T Lapatinib
0.12
uM
LJP6
 72
hr
 765 3026 3124 0.9685 0.9582
Hs 578T LDN-193189
0.12
uM
LJP5
 72
hr
 765 2856 3124 0.9143 0.8865
Hs 578T Linifanib
0.12
uM
LJP6
 72
hr
 765 3054 3124 0.9774 0.9701
Hs 578T Linsitinib
0.12
uM
LJP5
 72
hr
 765 3166 3124 1.0135 1.0179
Hs 578T Mitoxantrone
0.12
uM
LJP5
 72
hr
 765 698 3124 0.2236 -0.0281
Hs 578T Mitoxantrone
0.12
uM
LJP6
 72
hr
 765 669 3124 0.2141 -0.0407
Hs 578T MK2206
0.12
uM
LJP6
 72
hr
 765 2440 3124 0.7811 0.7102
Hs 578T Neratinib
0.12
uM
LJP5
 72
hr
 765 2591 3124 0.8294 0.7740
Hs 578T Nilotinib
0.12
uM
LJP5
 72
hr
 765 3572 3124 1.1432 1.1896