LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
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Hs 578T | A443654 | 0.12 | uM | LJP6 | 72 | hr | 765 | 1319 | 3124 | 0.4224 | 0.2351 |
Hs 578T | OSI-027 | 0.12 | uM | LJP6 | 72 | hr | 765 | 2766 | 3124 | 0.8854 | 0.8482 |
Hs 578T | XMD11-85h | 0.12 | uM | LJP6 | 72 | hr | 765 | 3132 | 3124 | 1.0025 | 1.0033 |
Hs 578T | HG-6-64-01 | 0.12 | uM | LJP6 | 72 | hr | 765 | 3351 | 3124 | 1.0725 | 1.0960 |
Hs 578T | WH-4-025 | 0.12 | uM | LJP5 | 72 | hr | 765 | 1798 | 3124 | 0.5756 | 0.4379 |
Hs 578T | WZ-4-145 | 0.12 | uM | LJP6 | 72 | hr | 765 | 2079 | 3124 | 0.6656 | 0.5572 |
Hs 578T | XMD16-144 | 0.12 | uM | LJP5 | 72 | hr | 765 | 828 | 3124 | 0.2650 | 0.0267 |
Hs 578T | Brivanib | 0.12 | uM | LJP5 | 72 | hr | 765 | 3068 | 3124 | 0.9819 | 0.9760 |
Hs 578T | Buparlisib | 0.12 | uM | LJP5 | 72 | hr | 765 | 2597 | 3124 | 0.8312 | 0.7764 |
Hs 578T | BX-912 | 0.12 | uM | LJP5 | 72 | hr | 765 | 2929 | 3124 | 0.9375 | 0.9173 |
Hs 578T | Canertinib | 0.12 | uM | LJP6 | 72 | hr | 765 | 3043 | 3124 | 0.9739 | 0.9654 |
Hs 578T | Celastrol | 0.12 | uM | LJP6 | 72 | hr | 765 | 3214 | 3124 | 1.0288 | 1.0382 |
Hs 578T | CGP60474 | 0.12 | uM | LJP5 | 72 | hr | 765 | 592 | 3124 | 0.1897 | -0.0731 |
Hs 578T | CGP60474 | 0.12 | uM | LJP6 | 72 | hr | 765 | 382 | 3124 | 0.1224 | -0.1622 |
Hs 578T | CHIR-99021 | 0.12 | uM | LJP6 | 72 | hr | 765 | 2981 | 3124 | 0.9543 | 0.9395 |
Hs 578T | CP724714 | 0.12 | uM | LJP5 | 72 | hr | 765 | 3139 | 3124 | 1.0046 | 1.0061 |
Hs 578T | CP466722 | 0.12 | uM | LJP5 | 72 | hr | 765 | 3222 | 3124 | 1.0313 | 1.0414 |
Hs 578T | Crizotinib | 0.12 | uM | LJP5 | 72 | hr | 765 | 3102 | 3124 | 0.9928 | 0.9905 |
Hs 578T | Momelotinib | 0.12 | uM | LJP5 | 72 | hr | 765 | 2751 | 3124 | 0.8806 | 0.8418 |
Hs 578T | Dasatinib | 0.12 | uM | LJP5 | 72 | hr | 765 | 1134 | 3124 | 0.3629 | 0.1564 |
Hs 578T | Dasatinib | 0.12 | uM | LJP6 | 72 | hr | 765 | 531 | 3124 | 0.1700 | -0.0992 |
Hs 578T | Dovitinib | 0.12 | uM | LJP5 | 72 | hr | 765 | 1856 | 3124 | 0.5941 | 0.4625 |
Hs 578T | Enzastaurin | 0.12 | uM | LJP5 | 72 | hr | 765 | 3078 | 3124 | 0.9852 | 0.9804 |
Hs 578T | Erlotinib | 0.12 | uM | LJP5 | 72 | hr | 765 | 3110 | 3124 | 0.9954 | 0.9938 |
Hs 578T | Foretinib | 0.12 | uM | LJP5 | 72 | hr | 765 | 2665 | 3124 | 0.8530 | 0.8054 |