LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | Afatinib | 10.0 | uM | LJP6 | 72 | hr | 1334 | 2081 | 3970 | 0.5242 | 0.2834 |
| BT-20 | Sigma A6730 | 10.0 | uM | LJP5 | 72 | hr | 1334 | 1867 | 3970 | 0.4703 | 0.2021 |
| BT-20 | Alvocidib | 10.0 | uM | LJP6 | 72 | hr | 1334 | 317 | 3970 | 0.0798 | -0.3860 |
| BT-20 | AT-7519 | 10.0 | uM | LJP6 | 72 | hr | 1334 | 285 | 3970 | 0.0719 | -0.3981 |
| BT-20 | AZD 5438 | 10.0 | uM | LJP6 | 72 | hr | 1334 | 407 | 3970 | 0.1027 | -0.3516 |
| BT-20 | AZD-6482 | 10.0 | uM | LJP5 | 72 | hr | 1334 | 1184 | 3970 | 0.2983 | -0.0569 |
| BT-20 | AZD7762 | 10.0 | uM | LJP6 | 72 | hr | 1334 | 417 | 3970 | 0.1052 | -0.3479 |
| BT-20 | AZD8055 | 10.0 | uM | LJP6 | 72 | hr | 1334 | 1052 | 3970 | 0.2649 | -0.1072 |
| BT-20 | AZD8330 | 10.0 | uM | LJP5 | 72 | hr | 1334 | 3412 | 3970 | 0.8593 | 0.7880 |
| BT-20 | Barasertib | 10.0 | uM | LJP5 | 72 | hr | 1334 | 999 | 3970 | 0.2518 | -0.1271 |
| BT-20 | BI-2536 | 10.0 | uM | LJP6 | 72 | hr | 1334 | 716 | 3970 | 0.1804 | -0.2346 |
| BT-20 | BMS345541 | 10.0 | uM | LJP6 | 72 | hr | 1334 | 1747 | 3970 | 0.4401 | 0.1567 |
| BT-20 | SNS-032 | 10.0 | uM | LJP6 | 72 | hr | 1334 | 422 | 3970 | 0.1063 | -0.3462 |
| BT-20 | GDC-0980 | 10.0 | uM | LJP5 | 72 | hr | 1334 | 857 | 3970 | 0.2160 | -0.1809 |
| BT-20 | NVP-AEW541 | 10.0 | uM | LJP5 | 72 | hr | 1334 | 3708 | 3970 | 0.9339 | 0.9004 |
| BT-20 | SB590885 | 10.0 | uM | LJP5 | 72 | hr | 1334 | 3603 | 3970 | 0.9074 | 0.8606 |
| BT-20 | PIK-93 | 10.0 | uM | LJP5 | 72 | hr | 1334 | 1431 | 3970 | 0.3605 | 0.0367 |
| BT-20 | KIN001-043 | 10.0 | uM | LJP6 | 72 | hr | 1334 | 3001 | 3970 | 0.7558 | 0.6321 |
| BT-20 | Alpelisib | 10.0 | uM | LJP5 | 72 | hr | 1334 | 917 | 3970 | 0.2309 | -0.1584 |
| BT-20 | Luminespib | 10.0 | uM | LJP5 | 72 | hr | 1334 | 1000 | 3970 | 0.2520 | -0.1267 |
| BT-20 | A443654 | 10.0 | uM | LJP6 | 72 | hr | 1334 | 232 | 3970 | 0.0586 | -0.4180 |
| BT-20 | OSI-027 | 10.0 | uM | LJP6 | 72 | hr | 1334 | 1653 | 3970 | 0.4163 | 0.1208 |
| BT-20 | XMD11-85h | 10.0 | uM | LJP6 | 72 | hr | 1334 | 3553 | 3970 | 0.8948 | 0.8415 |
| BT-20 | HG-6-64-01 | 10.0 | uM | LJP6 | 72 | hr | 1334 | 1475 | 3970 | 0.3715 | 0.0534 |
| BT-20 | WH-4-025 | 10.0 | uM | LJP5 | 72 | hr | 1334 | 676 | 3970 | 0.1702 | -0.2499 |