LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
BT-20 Radicicol
3.33
uM
LJP6
 72
hr
 1334 980 3970 0.2470 -0.1343
BT-20 Seliciclib
3.33
uM
LJP5
 72
hr
 1334 3442 3970 0.8668 0.7994
BT-20 Ruxolitinib
3.33
uM
LJP5
 72
hr
 1334 3901 3970 0.9825 0.9736
BT-20 XL147
3.33
uM
LJP5
 72
hr
 1334 3528 3970 0.8886 0.8322
BT-20 Saracatinib
3.33
uM
LJP6
 72
hr
 1334 3169 3970 0.7982 0.6961
BT-20 Selumetinib
3.33
uM
LJP6
 72
hr
 1334 3760 3970 0.9470 0.9201
BT-20 Sirolimus
3.33
uM
LJP6
 72
hr
 1334 2448 3970 0.6166 0.4224
BT-20 Sorafenib
3.33
uM
LJP6
 72
hr
 1334 3523 3970 0.8873 0.8302
BT-20 SU11274
3.33
uM
LJP5
 72
hr
 1334 3456 3970 0.8703 0.8047
BT-20 Fedratinib
3.33
uM
LJP5
 72
hr
 1334 2986 3970 0.7521 0.6265
BT-20 TGX221
3.33
uM
LJP5
 72
hr
 1334 4317 3970 1.0872 1.1313
BT-20 Torin1
3.33
uM
LJP6
 72
hr
 1334 1086 3970 0.2736 -0.0942
BT-20 Torin2
3.33
uM
LJP5
 72
hr
 1334 631 3970 0.1590 -0.2668
BT-20 Tozasertib
3.33
uM
LJP5
 72
hr
 1334 1025 3970 0.2581 -0.1175
BT-20 Trametinib
3.33
uM
LJP5
 72
hr
 1334 3106 3970 0.7823 0.6720
BT-20 TWS119
3.33
uM
LJP5
 72
hr
 1334 3239 3970 0.8158 0.7225
BT-20 Vemurafenib
3.33
uM
LJP5
 72
hr
 1334 3595 3970 0.9055 0.8577
BT-20 Withaferin A
3.33
uM
LJP5
 72
hr
 1334 647 3970 0.1629 -0.2609
BT-20 Withaferin A
3.33
uM
LJP6
 72
hr
 1334 504 3970 0.1271 -0.3149
BT-20 WYE-125132
3.33
uM
LJP6
 72
hr
 1334 1586 3970 0.3996 0.0956
BT-20 WZ3105
3.33
uM
LJP5
 72
hr
 1334 518 3970 0.1305 -0.3098
BT-20 XMD11-50
3.33
uM
LJP6
 72
hr
 1334 2989 3970 0.7527 0.6275
BT-20 Y39983
3.33
uM
LJP6
 72
hr
 1334 3643 3970 0.9175 0.8757
BT-20 YM 201636
3.33
uM
LJP5
 72
hr
 1334 2784 3970 0.7011 0.5498
BT-20 ZSTK474
3.33
uM
LJP6
 72
hr
 1334 1881 3970 0.4738 0.2074