LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
BT-20 Mitoxantrone
3.33
uM
LJP5
 72
hr
 1334 698 3970 0.1759 -0.2414
BT-20 Mitoxantrone
3.33
uM
LJP6
 72
hr
 1334 597 3970 0.1505 -0.2796
BT-20 MK2206
3.33
uM
LJP6
 72
hr
 1334 2979 3970 0.7504 0.6240
BT-20 Neratinib
3.33
uM
LJP5
 72
hr
 1334 2470 3970 0.6222 0.4309
BT-20 Nilotinib
3.33
uM
LJP5
 72
hr
 1334 4174 3970 1.0511 1.0770
BT-20 Nintedanib
3.33
uM
LJP6
 72
hr
 1334 2894 3970 0.7289 0.5916
BT-20 NU7441
3.33
uM
LJP5
 72
hr
 1334 3554 3970 0.8951 0.8420
BT-20 Dactolisib
3.33
uM
LJP5
 72
hr
 1334 1375 3970 0.3464 0.0154
BT-20 NVP-TAE684
3.33
uM
LJP6
 72
hr
 1334 3300 3970 0.8312 0.7458
BT-20 Palbociclib
3.33
uM
LJP6
 72
hr
 1334 2133 3970 0.5373 0.3031
BT-20 PD0325901
3.33
uM
LJP5
 72
hr
 1334 3046 3970 0.7673 0.6494
BT-20 PD0325901
3.33
uM
LJP6
 72
hr
 1334 2453 3970 0.6177 0.4242
BT-20 PD173074
3.33
uM
LJP6
 72
hr
 1334 4437 3970 1.1175 1.1771
BT-20 PD184352
3.33
uM
LJP5
 72
hr
 1334 3902 3970 0.9827 0.9739
BT-20 Pelitinib
3.33
uM
LJP5
 72
hr
 1334 2711 3970 0.6827 0.5221
BT-20 PF431396
3.33
uM
LJP5
 72
hr
 1334 1125 3970 0.2835 -0.0793
BT-20 PF477736
3.33
uM
LJP5
 72
hr
 1334 3255 3970 0.8198 0.7286
BT-20 PF562271
3.33
uM
LJP6
 72
hr
 1334 2176 3970 0.5481 0.3193
BT-20 PHA-665752
3.33
uM
LJP5
 72
hr
 1334 3854 3970 0.9706 0.9558
BT-20 PHA-793887
3.33
uM
LJP6
 72
hr
 1334 1478 3970 0.3723 0.0545
BT-20 PI103
3.33
uM
LJP6
 72
hr
 1334 1188 3970 0.2993 -0.0555
BT-20 PLX-4720
3.33
uM
LJP5
 72
hr
 1334 3389 3970 0.8536 0.7795
BT-20 QL-X-138
3.33
uM
LJP6
 72
hr
 1334 2711 3970 0.6829 0.5223
BT-20 QL-XII-47
3.33
uM
LJP6
 72
hr
 1334 1208 3970 0.3043 -0.0479
BT-20 Radicicol
3.33
uM
LJP5
 72
hr
 1334 954 3970 0.2403 -0.1443