LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
BT-20 R406
0.37
uM
LJP6
72
hr
1334 3747 3970 0.9437 0.9152
BT-20 Pictilisib
0.37
uM
LJP6
72
hr
1334 2996 3970 0.7546 0.6303
BT-20 Gefitinib
0.37
uM
LJP6
72
hr
1334 3831 3970 0.9649 0.9472
BT-20 Geldanamycin
0.37
uM
LJP5
72
hr
1334 1009 3970 0.2543 -0.1233
BT-20 Geldanamycin
0.37
uM
LJP6
72
hr
1334 991 3970 0.2496 -0.1304
BT-20 GSK1059615
0.37
uM
LJP5
72
hr
1334 1606 3970 0.4046 0.1032
BT-20 GSK1059615
0.37
uM
LJP6
72
hr
1334 2282 3970 0.5747 0.3594
BT-20 GSK1904529A
0.37
uM
LJP6
72
hr
1334 3680 3970 0.9268 0.8898
BT-20 Omipalisib
0.37
uM
LJP6
72
hr
1334 856 3970 0.2156 -0.1816
BT-20 GSK 690693
0.37
uM
LJP5
72
hr
1334 3024 3970 0.7616 0.6409
BT-20 GW843682X
0.37
uM
LJP6
72
hr
1334 2878 3970 0.7249 0.5857
BT-20 HG-5-113-01
0.37
uM
LJP5
72
hr
1334 3267 3970 0.8229 0.7332
BT-20 HG-5-88-01
0.37
uM
LJP6
72
hr
1334 3702 3970 0.9325 0.8983
BT-20 Imatinib
0.37
uM
LJP6
72
hr
1334 3798 3970 0.9565 0.9345
BT-20 JNK-9L
0.37
uM
LJP6
72
hr
1334 3591 3970 0.9044 0.8560
BT-20 JW-7-24-1
0.37
uM
LJP6
72
hr
1334 3620 3970 0.9116 0.8669
BT-20 Lapatinib
0.37
uM
LJP6
72
hr
1334 3896 3970 0.9812 0.9717
BT-20 LDN-193189
0.37
uM
LJP5
72
hr
1334 3952 3970 0.9953 0.9930
BT-20 Linifanib
0.37
uM
LJP6
72
hr
1334 4160 3970 1.0476 1.0717
BT-20 Linsitinib
0.37
uM
LJP5
72
hr
1334 4078 3970 1.0271 1.0409
BT-20 Mitoxantrone
0.37
uM
LJP5
72
hr
1334 777 3970 0.1958 -0.2114
BT-20 Mitoxantrone
0.37
uM
LJP6
72
hr
1334 954 3970 0.2403 -0.1444
BT-20 MK2206
0.37
uM
LJP6
72
hr
1334 3358 3970 0.8457 0.7676
BT-20 Neratinib
0.37
uM
LJP5
72
hr
1334 2977 3970 0.7499 0.6232
BT-20 Nilotinib
0.37
uM
LJP5
72
hr
1334 4227 3970 1.0646 1.0973