LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|
BT-20 | WZ-4-145 | 0.04 | uM | LJP6 | 72 | hr | 1334 | 3309 | 3970 | 0.8334 | 0.7490 |
BT-20 | XMD16-144 | 0.04 | uM | LJP5 | 72 | hr | 1334 | 3824 | 3970 | 0.9632 | 0.9445 |
BT-20 | Brivanib | 0.04 | uM | LJP5 | 72 | hr | 1334 | 4008 | 3970 | 1.0093 | 1.0141 |
BT-20 | Buparlisib | 0.04 | uM | LJP5 | 72 | hr | 1334 | 4150 | 3970 | 1.0451 | 1.0679 |
BT-20 | BX-912 | 0.04 | uM | LJP5 | 72 | hr | 1334 | 3739 | 3970 | 0.9417 | 0.9122 |
BT-20 | Canertinib | 0.04 | uM | LJP6 | 72 | hr | 1334 | 3494 | 3970 | 0.8801 | 0.8194 |
BT-20 | Celastrol | 0.04 | uM | LJP6 | 72 | hr | 1334 | 4023 | 3970 | 1.0132 | 1.0199 |
BT-20 | CGP60474 | 0.04 | uM | LJP5 | 72 | hr | 1334 | 3530 | 3970 | 0.8891 | 0.8329 |
BT-20 | CGP60474 | 0.04 | uM | LJP6 | 72 | hr | 1334 | 782 | 3970 | 0.1969 | -0.2097 |
BT-20 | CHIR-99021 | 0.04 | uM | LJP6 | 72 | hr | 1334 | 3515 | 3970 | 0.8853 | 0.8272 |
BT-20 | CP724714 | 0.04 | uM | LJP5 | 72 | hr | 1334 | 3801 | 3970 | 0.9572 | 0.9356 |
BT-20 | CP466722 | 0.04 | uM | LJP5 | 72 | hr | 1334 | 4240 | 3970 | 1.0678 | 1.1022 |
BT-20 | Crizotinib | 0.04 | uM | LJP5 | 72 | hr | 1334 | 3325 | 3970 | 0.8374 | 0.7551 |
BT-20 | Momelotinib | 0.04 | uM | LJP5 | 72 | hr | 1334 | 3991 | 3970 | 1.0051 | 1.0077 |
BT-20 | Dasatinib | 0.04 | uM | LJP5 | 72 | hr | 1334 | 3455 | 3970 | 0.8701 | 0.8043 |
BT-20 | Dasatinib | 0.04 | uM | LJP6 | 72 | hr | 1334 | 2913 | 3970 | 0.7337 | 0.5988 |
BT-20 | Dovitinib | 0.04 | uM | LJP5 | 72 | hr | 1334 | 3395 | 3970 | 0.8550 | 0.7815 |
BT-20 | Enzastaurin | 0.04 | uM | LJP5 | 72 | hr | 1334 | 3740 | 3970 | 0.9419 | 0.9125 |
BT-20 | Erlotinib | 0.04 | uM | LJP5 | 72 | hr | 1334 | 3679 | 3970 | 0.9267 | 0.8895 |
BT-20 | Foretinib | 0.04 | uM | LJP5 | 72 | hr | 1334 | 3950 | 3970 | 0.9948 | 0.9922 |
BT-20 | R406 | 0.04 | uM | LJP6 | 72 | hr | 1334 | 3713 | 3970 | 0.9351 | 0.9023 |
BT-20 | Pictilisib | 0.04 | uM | LJP6 | 72 | hr | 1334 | 3004 | 3970 | 0.7566 | 0.6334 |
BT-20 | Gefitinib | 0.04 | uM | LJP6 | 72 | hr | 1334 | 4187 | 3970 | 1.0546 | 1.0822 |
BT-20 | Geldanamycin | 0.04 | uM | LJP5 | 72 | hr | 1334 | 1781 | 3970 | 0.4486 | 0.1694 |
BT-20 | Geldanamycin | 0.04 | uM | LJP6 | 72 | hr | 1334 | 2191 | 3970 | 0.5519 | 0.3251 |