LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T PI103
0.04
uM
LJP6
 72
hr
 765 2309 3124 0.7390 0.6544
Hs 578T PLX-4720
0.04
uM
LJP5
 72
hr
 765 3161 3124 1.0117 1.0155
Hs 578T QL-X-138
0.04
uM
LJP6
 72
hr
 765 2546 3124 0.8148 0.7548
Hs 578T QL-XII-47
0.04
uM
LJP6
 72
hr
 765 2960 3124 0.9473 0.9303
Hs 578T Radicicol
0.04
uM
LJP5
 72
hr
 765 3225 3124 1.0323 1.0427
Hs 578T Radicicol
0.04
uM
LJP6
 72
hr
 765 3176 3124 1.0166 1.0220
Hs 578T Seliciclib
0.04
uM
LJP5
 72
hr
 765 3140 3124 1.0049 1.0066
Hs 578T Ruxolitinib
0.04
uM
LJP5
 72
hr
 765 3133 3124 1.0027 1.0036
Hs 578T XL147
0.04
uM
LJP5
 72
hr
 765 3060 3124 0.9793 0.9727
Hs 578T Saracatinib
0.04
uM
LJP6
 72
hr
 765 3080 3124 0.9860 0.9814
Hs 578T Selumetinib
0.04
uM
LJP6
 72
hr
 765 2071 3124 0.6630 0.5538
Hs 578T Sirolimus
0.04
uM
LJP6
 72
hr
 765 1832 3124 0.5863 0.4522
Hs 578T Sorafenib
0.04
uM
LJP6
 72
hr
 765 3596 3124 1.1509 1.1998
Hs 578T SU11274
0.04
uM
LJP5
 72
hr
 765 3235 3124 1.0354 1.0468
Hs 578T Fedratinib
0.04
uM
LJP5
 72
hr
 765 3204 3124 1.0254 1.0337
Hs 578T TGX221
0.04
uM
LJP5
 72
hr
 765 2905 3124 0.9298 0.9071
Hs 578T Torin1
0.04
uM
LJP6
 72
hr
 765 1096 3124 0.3508 0.1403
Hs 578T Torin2
0.04
uM
LJP5
 72
hr
 765 1013 3124 0.3242 0.1051
Hs 578T Tozasertib
0.04
uM
LJP5
 72
hr
 765 841 3124 0.2692 0.0322
Hs 578T Trametinib
0.04
uM
LJP5
 72
hr
 765 1192 3124 0.3816 0.1811
Hs 578T TWS119
0.04
uM
LJP5
 72
hr
 765 3150 3124 1.0081 1.0108
Hs 578T Vemurafenib
0.04
uM
LJP5
 72
hr
 765 3316 3124 1.0613 1.0811
Hs 578T Withaferin A
0.04
uM
LJP5
 72
hr
 765 3121 3124 0.9989 0.9985
Hs 578T Withaferin A
0.04
uM
LJP6
 72
hr
 765 3074 3124 0.9840 0.9789
Hs 578T WYE-125132
0.04
uM
LJP6
 72
hr
 765 1084 3124 0.3471 0.1355