LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T TWS119
0.37
uM
LJP5
 72
hr
 765 3044 3124 0.9744 0.9662
Hs 578T Vemurafenib
0.37
uM
LJP5
 72
hr
 765 3287 3124 1.0520 1.0689
Hs 578T Withaferin A
0.37
uM
LJP5
 72
hr
 765 2998 3124 0.9595 0.9464
Hs 578T Withaferin A
0.37
uM
LJP6
 72
hr
 765 2903 3124 0.9292 0.9063
Hs 578T WYE-125132
0.37
uM
LJP6
 72
hr
 765 923 3124 0.2954 0.0669
Hs 578T WZ3105
0.37
uM
LJP5
 72
hr
 765 447 3124 0.1432 -0.1347
Hs 578T XMD11-50
0.37
uM
LJP6
 72
hr
 765 2638 3124 0.8443 0.7938
Hs 578T Y39983
0.37
uM
LJP6
 72
hr
 765 2484 3124 0.7952 0.7288
Hs 578T YM 201636
0.37
uM
LJP5
 72
hr
 765 2958 3124 0.9469 0.9297
Hs 578T ZSTK474
0.37
uM
LJP6
 72
hr
 765 1696 3124 0.5429 0.3947
Hs 578T Afatinib
1.11
uM
LJP6
 72
hr
 765 2709 3124 0.8671 0.8240
Hs 578T Sigma A6730
1.11
uM
LJP5
 72
hr
 765 2613 3124 0.8364 0.7833
Hs 578T Alvocidib
1.11
uM
LJP6
 72
hr
 765 349 3124 0.1118 -0.1762
Hs 578T AT-7519
1.11
uM
LJP6
 72
hr
 765 445 3124 0.1426 -0.1354
Hs 578T AZD 5438
1.11
uM
LJP6
 72
hr
 765 728 3124 0.2331 -0.0156
Hs 578T AZD-6482
1.11
uM
LJP5
 72
hr
 765 2358 3124 0.7548 0.6753
Hs 578T AZD7762
1.11
uM
LJP6
 72
hr
 765 497 3124 0.1593 -0.1133
Hs 578T AZD8055
1.11
uM
LJP6
 72
hr
 765 1035 3124 0.3314 0.1146
Hs 578T AZD8330
1.11
uM
LJP5
 72
hr
 765 972 3124 0.3111 0.0877
Hs 578T Barasertib
1.11
uM
LJP5
 72
hr
 765 1005 3124 0.3219 0.1020
Hs 578T BI-2536
1.11
uM
LJP6
 72
hr
 765 504 3124 0.1614 -0.1105
Hs 578T BMS345541
1.11
uM
LJP6
 72
hr
 765 2882 3124 0.9226 0.8975
Hs 578T SNS-032
1.11
uM
LJP6
 72
hr
 765 379 3124 0.1215 -0.1633
Hs 578T GDC-0980
1.11
uM
LJP5
 72
hr
 765 882 3124 0.2823 0.0496
Hs 578T NVP-AEW541
1.11
uM
LJP5
 72
hr
 765 3168 3124 1.0141 1.0187