LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | BI-2536 | 10.0 | uM | LJP6 | 72 | hr | 765 | 401 | 3124 | 0.1283 | -0.1543 |
| Hs 578T | BMS345541 | 10.0 | uM | LJP6 | 72 | hr | 765 | 349 | 3124 | 0.1117 | -0.1763 |
| Hs 578T | SNS-032 | 10.0 | uM | LJP6 | 72 | hr | 765 | 399 | 3124 | 0.1279 | -0.1549 |
| Hs 578T | GDC-0980 | 10.0 | uM | LJP5 | 72 | hr | 765 | 728 | 3124 | 0.2331 | -0.0156 |
| Hs 578T | NVP-AEW541 | 10.0 | uM | LJP5 | 72 | hr | 765 | 647 | 3124 | 0.2071 | -0.0500 |
| Hs 578T | SB590885 | 10.0 | uM | LJP5 | 72 | hr | 765 | 1092 | 3124 | 0.3496 | 0.1387 |
| Hs 578T | PIK-93 | 10.0 | uM | LJP5 | 72 | hr | 765 | 685 | 3124 | 0.2192 | -0.0339 |
| Hs 578T | KIN001-043 | 10.0 | uM | LJP6 | 72 | hr | 765 | 1194 | 3124 | 0.3821 | 0.1818 |
| Hs 578T | Alpelisib | 10.0 | uM | LJP5 | 72 | hr | 765 | 1757 | 3124 | 0.5623 | 0.4204 |
| Hs 578T | Luminespib | 10.0 | uM | LJP5 | 72 | hr | 765 | 690 | 3124 | 0.2209 | -0.0317 |
| Hs 578T | A443654 | 10.0 | uM | LJP6 | 72 | hr | 765 | 269 | 3124 | 0.0862 | -0.2101 |
| Hs 578T | OSI-027 | 10.0 | uM | LJP6 | 72 | hr | 765 | 882 | 3124 | 0.2824 | 0.0497 |
| Hs 578T | XMD11-85h | 10.0 | uM | LJP6 | 72 | hr | 765 | 1235 | 3124 | 0.3954 | 0.1993 |
| Hs 578T | HG-6-64-01 | 10.0 | uM | LJP6 | 72 | hr | 765 | 174 | 3124 | 0.0559 | -0.2502 |
| Hs 578T | WH-4-025 | 10.0 | uM | LJP5 | 72 | hr | 765 | 226 | 3124 | 0.0723 | -0.2285 |
| Hs 578T | WZ-4-145 | 10.0 | uM | LJP6 | 72 | hr | 765 | 713 | 3124 | 0.2284 | -0.0218 |
| Hs 578T | XMD16-144 | 10.0 | uM | LJP5 | 72 | hr | 765 | 361 | 3124 | 0.1155 | -0.1712 |
| Hs 578T | Brivanib | 10.0 | uM | LJP5 | 72 | hr | 765 | 2616 | 3124 | 0.8375 | 0.7848 |
| Hs 578T | Buparlisib | 10.0 | uM | LJP5 | 72 | hr | 765 | 331 | 3124 | 0.1059 | -0.1840 |
| Hs 578T | BX-912 | 10.0 | uM | LJP5 | 72 | hr | 765 | 415 | 3124 | 0.1329 | -0.1482 |
| Hs 578T | Canertinib | 10.0 | uM | LJP6 | 72 | hr | 765 | 240 | 3124 | 0.0770 | -0.2222 |
| Hs 578T | Celastrol | 10.0 | uM | LJP6 | 72 | hr | 765 | 461 | 3124 | 0.1475 | -0.1289 |
| Hs 578T | CGP60474 | 10.0 | uM | LJP5 | 72 | hr | 765 | 428 | 3124 | 0.1370 | -0.1429 |
| Hs 578T | CGP60474 | 10.0 | uM | LJP6 | 72 | hr | 765 | 218 | 3124 | 0.0698 | -0.2319 |
| Hs 578T | CHIR-99021 | 10.0 | uM | LJP6 | 72 | hr | 765 | 1478 | 3124 | 0.4731 | 0.3023 |