LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | CP724714 | 10.0 | uM | LJP5 | 72 | hr | 765 | 2647 | 3124 | 0.8472 | 0.7976 |
| Hs 578T | CP466722 | 10.0 | uM | LJP5 | 72 | hr | 765 | 2615 | 3124 | 0.8370 | 0.7842 |
| Hs 578T | Crizotinib | 10.0 | uM | LJP5 | 72 | hr | 765 | 662 | 3124 | 0.2119 | -0.0437 |
| Hs 578T | Momelotinib | 10.0 | uM | LJP5 | 72 | hr | 765 | 754 | 3124 | 0.2413 | -0.0047 |
| Hs 578T | Dasatinib | 10.0 | uM | LJP5 | 72 | hr | 765 | 480 | 3124 | 0.1537 | -0.1207 |
| Hs 578T | Dasatinib | 10.0 | uM | LJP6 | 72 | hr | 765 | 354 | 3124 | 0.1133 | -0.1742 |
| Hs 578T | Dovitinib | 10.0 | uM | LJP5 | 72 | hr | 765 | 1157 | 3124 | 0.3705 | 0.1664 |
| Hs 578T | Enzastaurin | 10.0 | uM | LJP5 | 72 | hr | 765 | 3043 | 3124 | 0.9739 | 0.9654 |
| Hs 578T | Erlotinib | 10.0 | uM | LJP5 | 72 | hr | 765 | 1776 | 3124 | 0.5686 | 0.4287 |
| Hs 578T | Foretinib | 10.0 | uM | LJP5 | 72 | hr | 765 | 302 | 3124 | 0.0967 | -0.1963 |
| Hs 578T | R406 | 10.0 | uM | LJP6 | 72 | hr | 765 | 646 | 3124 | 0.2070 | -0.0502 |
| Hs 578T | Pictilisib | 10.0 | uM | LJP6 | 72 | hr | 765 | 1063 | 3124 | 0.3402 | 0.1263 |
| Hs 578T | Gefitinib | 10.0 | uM | LJP6 | 72 | hr | 765 | 2677 | 3124 | 0.8568 | 0.8103 |
| Hs 578T | Geldanamycin | 10.0 | uM | LJP5 | 72 | hr | 765 | 344 | 3124 | 0.1103 | -0.1782 |
| Hs 578T | Geldanamycin | 10.0 | uM | LJP6 | 72 | hr | 765 | 410 | 3124 | 0.1313 | -0.1503 |
| Hs 578T | GSK1059615 | 10.0 | uM | LJP5 | 72 | hr | 765 | 590 | 3124 | 0.1889 | -0.0740 |
| Hs 578T | GSK1059615 | 10.0 | uM | LJP6 | 72 | hr | 765 | 698 | 3124 | 0.2234 | -0.0284 |
| Hs 578T | GSK1904529A | 10.0 | uM | LJP6 | 72 | hr | 765 | 2905 | 3124 | 0.9298 | 0.9071 |
| Hs 578T | Omipalisib | 10.0 | uM | LJP6 | 72 | hr | 765 | 358 | 3124 | 0.1147 | -0.1724 |
| Hs 578T | GSK 690693 | 10.0 | uM | LJP5 | 72 | hr | 765 | 2102 | 3124 | 0.6730 | 0.5669 |
| Hs 578T | GW843682X | 10.0 | uM | LJP6 | 72 | hr | 765 | 450 | 3124 | 0.1442 | -0.1332 |
| Hs 578T | HG-5-113-01 | 10.0 | uM | LJP5 | 72 | hr | 765 | 631 | 3124 | 0.2022 | -0.0565 |
| Hs 578T | HG-5-88-01 | 10.0 | uM | LJP6 | 72 | hr | 765 | 2098 | 3124 | 0.6715 | 0.5649 |
| Hs 578T | Imatinib | 10.0 | uM | LJP6 | 72 | hr | 765 | 3387 | 3124 | 1.0840 | 1.1112 |
| Hs 578T | JNK-9L | 10.0 | uM | LJP6 | 72 | hr | 765 | 531 | 3124 | 0.1700 | -0.0992 |