LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T JW-7-24-1
10.0
uM
LJP6
 72
hr
 765 414 3124 0.1326 -0.1486
Hs 578T Lapatinib
10.0
uM
LJP6
 72
hr
 765 2210 3124 0.7073 0.6124
Hs 578T LDN-193189
10.0
uM
LJP5
 72
hr
 765 230 3124 0.0738 -0.2265
Hs 578T Linifanib
10.0
uM
LJP6
 72
hr
 765 2587 3124 0.8280 0.7722
Hs 578T Linsitinib
10.0
uM
LJP5
 72
hr
 765 2514 3124 0.8047 0.7414
Hs 578T Mitoxantrone
10.0
uM
LJP5
 72
hr
 765 172 3124 0.0550 -0.2514
Hs 578T Mitoxantrone
10.0
uM
LJP6
 72
hr
 765 208 3124 0.0668 -0.2358
Hs 578T MK2206
10.0
uM
LJP6
 72
hr
 765 2324 3124 0.7438 0.6607
Hs 578T Neratinib
10.0
uM
LJP5
 72
hr
 765 1001 3124 0.3205 0.1001
Hs 578T Nilotinib
10.0
uM
LJP5
 72
hr
 765 662 3124 0.2121 -0.0434
Hs 578T Nintedanib
10.0
uM
LJP6
 72
hr
 765 1168 3124 0.3739 0.1709
Hs 578T NU7441
10.0
uM
LJP5
 72
hr
 765 1183 3124 0.3786 0.1771
Hs 578T Dactolisib
10.0
uM
LJP5
 72
hr
 765 893 3124 0.2859 0.0544
Hs 578T NVP-TAE684
10.0
uM
LJP6
 72
hr
 765 531 3124 0.1702 -0.0989
Hs 578T Palbociclib
10.0
uM
LJP6
 72
hr
 765 1377 3124 0.4408 0.2595
Hs 578T PD0325901
10.0
uM
LJP5
 72
hr
 765 643 3124 0.2060 -0.0514
Hs 578T PD0325901
10.0
uM
LJP6
 72
hr
 765 690 3124 0.2211 -0.0315
Hs 578T PD173074
10.0
uM
LJP6
 72
hr
 765 828 3124 0.2651 0.0268
Hs 578T PD184352
10.0
uM
LJP5
 72
hr
 765 1137 3124 0.3641 0.1579
Hs 578T Pelitinib
10.0
uM
LJP5
 72
hr
 765 628 3124 0.2011 -0.0579
Hs 578T PF431396
10.0
uM
LJP5
 72
hr
 765 489 3124 0.1566 -0.1169
Hs 578T PF477736
10.0
uM
LJP5
 72
hr
 765 446 3124 0.1430 -0.1349
Hs 578T PF562271
10.0
uM
LJP6
 72
hr
 765 461 3124 0.1478 -0.1286
Hs 578T PHA-665752
10.0
uM
LJP5
 72
hr
 765 395 3124 0.1266 -0.1566
Hs 578T PHA-793887
10.0
uM
LJP6
 72
hr
 765 397 3124 0.1272 -0.1559