LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A PF431396
0.12
uM
LJP5
 72
hr
 1694 5698 11155 0.5108 0.4232
MCF 10A PF477736
0.12
uM
LJP5
 72
hr
 1694 10046 11155 0.9006 0.8828
MCF 10A PF562271
0.12
uM
LJP6
 72
hr
 1694 8613 11155 0.7721 0.7313
MCF 10A PHA-665752
0.12
uM
LJP5
 72
hr
 1694 10792 11155 0.9674 0.9616
MCF 10A PHA-793887
0.12
uM
LJP6
 72
hr
 1694 3384 11155 0.3034 0.1786
MCF 10A PI103
0.12
uM
LJP6
 72
hr
 1694 11398 11155 1.0218 1.0257
MCF 10A PLX-4720
0.12
uM
LJP5
 72
hr
 1694 11028 11155 0.9886 0.9865
MCF 10A QL-X-138
0.12
uM
LJP6
 72
hr
 1694 12035 11155 1.0789 1.0930
MCF 10A QL-XII-47
0.12
uM
LJP6
 72
hr
 1694 10935 11155 0.9802 0.9767
MCF 10A Radicicol
0.12
uM
LJP5
 72
hr
 1694 7622 11155 0.6833 0.6266
MCF 10A Radicicol
0.12
uM
LJP6
 72
hr
 1694 7232 11155 0.6483 0.5853
MCF 10A Seliciclib
0.12
uM
LJP5
 72
hr
 1694 10898 11155 0.9769 0.9728
MCF 10A Ruxolitinib
0.12
uM
LJP5
 72
hr
 1694 11068 11155 0.9922 0.9908
MCF 10A XL147
0.12
uM
LJP5
 72
hr
 1694 10818 11155 0.9697 0.9643
MCF 10A Saracatinib
0.12
uM
LJP6
 72
hr
 1694 10704 11155 0.9595 0.9523
MCF 10A Selumetinib
0.12
uM
LJP6
 72
hr
 1694 4842 11155 0.4341 0.3327
MCF 10A Sirolimus
0.12
uM
LJP6
 72
hr
 1694 12338 11155 1.1060 1.1250
MCF 10A Sorafenib
0.12
uM
LJP6
 72
hr
 1694 11824 11155 1.0600 1.0707
MCF 10A SU11274
0.12
uM
LJP5
 72
hr
 1694 10937 11155 0.9804 0.9769
MCF 10A Fedratinib
0.12
uM
LJP5
 72
hr
 1694 10674 11155 0.9568 0.9491
MCF 10A TGX221
0.12
uM
LJP5
 72
hr
 1694 10876 11155 0.9750 0.9705
MCF 10A Torin1
0.12
uM
LJP6
 72
hr
 1694 3778 11155 0.3387 0.2203
MCF 10A Torin2
0.12
uM
LJP5
 72
hr
 1694 2733 11155 0.2450 0.1098
MCF 10A Tozasertib
0.12
uM
LJP5
 72
hr
 1694 2001 11155 0.1794 0.0324
MCF 10A Trametinib
0.12
uM
LJP5
 72
hr
 1694 2983 11155 0.2675 0.1363