LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | TGX221 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 10748 | 11155 | 0.9635 | 0.9569 |
| MCF 10A | Torin1 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 2501 | 11155 | 0.2243 | 0.0853 |
| MCF 10A | Torin2 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 2122 | 11155 | 0.1902 | 0.0452 |
| MCF 10A | Tozasertib | 1.11 | uM | LJP5 | 72 | hr | 1694 | 1973 | 11155 | 0.1769 | 0.0295 |
| MCF 10A | Trametinib | 1.11 | uM | LJP5 | 72 | hr | 1694 | 3255 | 11155 | 0.2918 | 0.1650 |
| MCF 10A | TWS119 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 11701 | 11155 | 1.0489 | 1.0577 |
| MCF 10A | Vemurafenib | 1.11 | uM | LJP5 | 72 | hr | 1694 | 10870 | 11155 | 0.9745 | 0.9699 |
| MCF 10A | Withaferin A | 1.11 | uM | LJP5 | 72 | hr | 1694 | 1248 | 11155 | 0.1119 | -0.0471 |
| MCF 10A | Withaferin A | 1.11 | uM | LJP6 | 72 | hr | 1694 | 1079 | 11155 | 0.0968 | -0.0650 |
| MCF 10A | WYE-125132 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 2743 | 11155 | 0.2459 | 0.1109 |
| MCF 10A | WZ3105 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 426 | 11155 | 0.0382 | -0.1340 |
| MCF 10A | XMD11-50 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 7854 | 11155 | 0.7041 | 0.6511 |
| MCF 10A | Y39983 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 9085 | 11155 | 0.8144 | 0.7812 |
| MCF 10A | YM 201636 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 8880 | 11155 | 0.7961 | 0.7596 |
| MCF 10A | ZSTK474 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 5606 | 11155 | 0.5026 | 0.4135 |
| MCF 10A | Afatinib | 3.33 | uM | LJP6 | 72 | hr | 1694 | 1868 | 11155 | 0.1675 | 0.0184 |
| MCF 10A | Sigma A6730 | 3.33 | uM | LJP5 | 72 | hr | 1694 | 11000 | 11155 | 0.9861 | 0.9836 |
| MCF 10A | Alvocidib | 3.33 | uM | LJP6 | 72 | hr | 1694 | 289 | 11155 | 0.0260 | -0.1485 |
| MCF 10A | AT-7519 | 3.33 | uM | LJP6 | 72 | hr | 1694 | 314 | 11155 | 0.0282 | -0.1459 |
| MCF 10A | AZD 5438 | 3.33 | uM | LJP6 | 72 | hr | 1694 | 513 | 11155 | 0.0460 | -0.1248 |
| MCF 10A | AZD-6482 | 3.33 | uM | LJP5 | 72 | hr | 1694 | 9430 | 11155 | 0.8454 | 0.8177 |
| MCF 10A | AZD7762 | 3.33 | uM | LJP6 | 72 | hr | 1694 | 3091 | 11155 | 0.2771 | 0.1477 |
| MCF 10A | AZD8055 | 3.33 | uM | LJP6 | 72 | hr | 1694 | 2536 | 11155 | 0.2273 | 0.0890 |
| MCF 10A | AZD8330 | 3.33 | uM | LJP5 | 72 | hr | 1694 | 2695 | 11155 | 0.2416 | 0.1058 |
| MCF 10A | Barasertib | 3.33 | uM | LJP5 | 72 | hr | 1694 | 2090 | 11155 | 0.1874 | 0.0419 |