LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | PD0325901 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 3004 | 11155 | 0.2693 | 0.1385 |
| MCF 10A | PD0325901 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 2609 | 11155 | 0.2339 | 0.0968 |
| MCF 10A | PD173074 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 10984 | 11155 | 0.9847 | 0.9819 |
| MCF 10A | PD184352 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 4073 | 11155 | 0.3651 | 0.2515 |
| MCF 10A | Pelitinib | 1.11 | uM | LJP5 | 72 | hr | 1694 | 2615 | 11155 | 0.2344 | 0.0974 |
| MCF 10A | PF431396 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 2245 | 11155 | 0.2013 | 0.0582 |
| MCF 10A | PF477736 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 7219 | 11155 | 0.6472 | 0.5840 |
| MCF 10A | PF562271 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 5198 | 11155 | 0.4660 | 0.3704 |
| MCF 10A | PHA-665752 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 10464 | 11155 | 0.9380 | 0.9269 |
| MCF 10A | PHA-793887 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 2252 | 11155 | 0.2019 | 0.0589 |
| MCF 10A | PI103 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 3253 | 11155 | 0.2916 | 0.1648 |
| MCF 10A | PLX-4720 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 11583 | 11155 | 1.0384 | 1.0452 |
| MCF 10A | QL-X-138 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 11078 | 11155 | 0.9930 | 0.9918 |
| MCF 10A | QL-XII-47 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 10063 | 11155 | 0.9021 | 0.8846 |
| MCF 10A | Radicicol | 1.11 | uM | LJP5 | 72 | hr | 1694 | 2365 | 11155 | 0.2120 | 0.0709 |
| MCF 10A | Radicicol | 1.11 | uM | LJP6 | 72 | hr | 1694 | 2358 | 11155 | 0.2114 | 0.0702 |
| MCF 10A | Seliciclib | 1.11 | uM | LJP5 | 72 | hr | 1694 | 10536 | 11155 | 0.9445 | 0.9346 |
| MCF 10A | Ruxolitinib | 1.11 | uM | LJP5 | 72 | hr | 1694 | 10633 | 11155 | 0.9532 | 0.9448 |
| MCF 10A | XL147 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 10115 | 11155 | 0.9067 | 0.8900 |
| MCF 10A | Saracatinib | 1.11 | uM | LJP6 | 72 | hr | 1694 | 7988 | 11155 | 0.7161 | 0.6652 |
| MCF 10A | Selumetinib | 1.11 | uM | LJP6 | 72 | hr | 1694 | 3467 | 11155 | 0.3108 | 0.1874 |
| MCF 10A | Sirolimus | 1.11 | uM | LJP6 | 72 | hr | 1694 | 12479 | 11155 | 1.1187 | 1.1399 |
| MCF 10A | Sorafenib | 1.11 | uM | LJP6 | 72 | hr | 1694 | 11015 | 11155 | 0.9874 | 0.9852 |
| MCF 10A | SU11274 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 9103 | 11155 | 0.8161 | 0.7831 |
| MCF 10A | Fedratinib | 1.11 | uM | LJP5 | 72 | hr | 1694 | 9912 | 11155 | 0.8886 | 0.8686 |