LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A GW843682X
0.12
uM
LJP6
 72
hr
 1694 9876 11155 0.8854 0.8648
MCF 10A HG-5-113-01
0.12
uM
LJP5
 72
hr
 1694 9608 11155 0.8613 0.8365
MCF 10A HG-5-88-01
0.12
uM
LJP6
 72
hr
 1694 9945 11155 0.8915 0.8721
MCF 10A Imatinib
0.12
uM
LJP6
 72
hr
 1694 11251 11155 1.0085 1.0101
MCF 10A JNK-9L
0.12
uM
LJP6
 72
hr
 1694 10724 11155 0.9613 0.9544
MCF 10A JW-7-24-1
0.12
uM
LJP6
 72
hr
 1694 11636 11155 1.0431 1.0508
MCF 10A Lapatinib
0.12
uM
LJP6
 72
hr
 1694 10440 11155 0.9359 0.9244
MCF 10A LDN-193189
0.12
uM
LJP5
 72
hr
 1694 10887 11155 0.9760 0.9716
MCF 10A Linifanib
0.12
uM
LJP6
 72
hr
 1694 11792 11155 1.0570 1.0673
MCF 10A Linsitinib
0.12
uM
LJP5
 72
hr
 1694 9752 11155 0.8742 0.8517
MCF 10A Mitoxantrone
0.12
uM
LJP5
 72
hr
 1694 1687 11155 0.1512 -0.0008
MCF 10A Mitoxantrone
0.12
uM
LJP6
 72
hr
 1694 1599 11155 0.1433 -0.0101
MCF 10A MK2206
0.12
uM
LJP6
 72
hr
 1694 11362 11155 1.0186 1.0219
MCF 10A Neratinib
0.12
uM
LJP5
 72
hr
 1694 4371 11155 0.3919 0.2830
MCF 10A Nilotinib
0.12
uM
LJP5
 72
hr
 1694 11259 11155 1.0093 1.0109
MCF 10A Nintedanib
0.12
uM
LJP6
 72
hr
 1694 10974 11155 0.9838 0.9808
MCF 10A NU7441
0.12
uM
LJP5
 72
hr
 1694 11065 11155 0.9919 0.9905
MCF 10A Dactolisib
0.12
uM
LJP5
 72
hr
 1694 4098 11155 0.3674 0.2541
MCF 10A NVP-TAE684
0.12
uM
LJP6
 72
hr
 1694 9404 11155 0.8430 0.8149
MCF 10A Palbociclib
0.12
uM
LJP6
 72
hr
 1694 8038 11155 0.7206 0.6705
MCF 10A PD0325901
0.12
uM
LJP5
 72
hr
 1694 3046 11155 0.2731 0.1429
MCF 10A PD0325901
0.12
uM
LJP6
 72
hr
 1694 3039 11155 0.2725 0.1422
MCF 10A PD173074
0.12
uM
LJP6
 72
hr
 1694 11343 11155 1.0168 1.0198
MCF 10A PD184352
0.12
uM
LJP5
 72
hr
 1694 5517 11155 0.4946 0.4040
MCF 10A Pelitinib
0.12
uM
LJP5
 72
hr
 1694 5807 11155 0.5206 0.4347