LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | Canertinib | 0.12 | uM | LJP6 | 72 | hr | 1694 | 6493 | 11155 | 0.5820 | 0.5072 |
MCF 10A | Celastrol | 0.12 | uM | LJP6 | 72 | hr | 1694 | 12410 | 11155 | 1.1125 | 1.1326 |
MCF 10A | CGP60474 | 0.12 | uM | LJP5 | 72 | hr | 1694 | 679 | 11155 | 0.0609 | -0.1073 |
MCF 10A | CGP60474 | 0.12 | uM | LJP6 | 72 | hr | 1694 | 306 | 11155 | 0.0275 | -0.1467 |
MCF 10A | CHIR-99021 | 0.12 | uM | LJP6 | 72 | hr | 1694 | 11662 | 11155 | 1.0454 | 1.0535 |
MCF 10A | CP724714 | 0.12 | uM | LJP5 | 72 | hr | 1694 | 10955 | 11155 | 0.9820 | 0.9788 |
MCF 10A | CP466722 | 0.12 | uM | LJP5 | 72 | hr | 1694 | 11356 | 11155 | 1.0180 | 1.0212 |
MCF 10A | Crizotinib | 0.12 | uM | LJP5 | 72 | hr | 1694 | 10549 | 11155 | 0.9456 | 0.9359 |
MCF 10A | Momelotinib | 0.12 | uM | LJP5 | 72 | hr | 1694 | 10139 | 11155 | 0.9089 | 0.8926 |
MCF 10A | Dasatinib | 0.12 | uM | LJP5 | 72 | hr | 1694 | 6014 | 11155 | 0.5392 | 0.4566 |
MCF 10A | Dasatinib | 0.12 | uM | LJP6 | 72 | hr | 1694 | 3709 | 11155 | 0.3325 | 0.2129 |
MCF 10A | Dovitinib | 0.12 | uM | LJP5 | 72 | hr | 1694 | 9580 | 11155 | 0.8588 | 0.8335 |
MCF 10A | Enzastaurin | 0.12 | uM | LJP5 | 72 | hr | 1694 | 11143 | 11155 | 0.9989 | 0.9987 |
MCF 10A | Erlotinib | 0.12 | uM | LJP5 | 72 | hr | 1694 | 9664 | 11155 | 0.8664 | 0.8424 |
MCF 10A | Foretinib | 0.12 | uM | LJP5 | 72 | hr | 1694 | 11382 | 11155 | 1.0203 | 1.0240 |
MCF 10A | R406 | 0.12 | uM | LJP6 | 72 | hr | 1694 | 11292 | 11155 | 1.0122 | 1.0144 |
MCF 10A | Pictilisib | 0.12 | uM | LJP6 | 72 | hr | 1694 | 9285 | 11155 | 0.8323 | 0.8023 |
MCF 10A | Gefitinib | 0.12 | uM | LJP6 | 72 | hr | 1694 | 6990 | 11155 | 0.6266 | 0.5598 |
MCF 10A | Geldanamycin | 0.12 | uM | LJP5 | 72 | hr | 1694 | 1651 | 11155 | 0.1481 | -0.0045 |
MCF 10A | Geldanamycin | 0.12 | uM | LJP6 | 72 | hr | 1694 | 1293 | 11155 | 0.1160 | -0.0423 |
MCF 10A | GSK1059615 | 0.12 | uM | LJP5 | 72 | hr | 1694 | 10702 | 11155 | 0.9593 | 0.9521 |
MCF 10A | GSK1059615 | 0.12 | uM | LJP6 | 72 | hr | 1694 | 9624 | 11155 | 0.8627 | 0.8382 |
MCF 10A | GSK1904529A | 0.12 | uM | LJP6 | 72 | hr | 1694 | 7248 | 11155 | 0.6497 | 0.5870 |
MCF 10A | Omipalisib | 0.12 | uM | LJP6 | 72 | hr | 1694 | 1837 | 11155 | 0.1647 | 0.0151 |
MCF 10A | GSK 690693 | 0.12 | uM | LJP5 | 72 | hr | 1694 | 11154 | 11155 | 0.9999 | 0.9998 |