LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A Canertinib
0.12
uM
LJP6
72
hr
1694 6493 11155 0.5820 0.5072
MCF 10A Celastrol
0.12
uM
LJP6
72
hr
1694 12410 11155 1.1125 1.1326
MCF 10A CGP60474
0.12
uM
LJP5
72
hr
1694 679 11155 0.0609 -0.1073
MCF 10A CGP60474
0.12
uM
LJP6
72
hr
1694 306 11155 0.0275 -0.1467
MCF 10A CHIR-99021
0.12
uM
LJP6
72
hr
1694 11662 11155 1.0454 1.0535
MCF 10A CP724714
0.12
uM
LJP5
72
hr
1694 10955 11155 0.9820 0.9788
MCF 10A CP466722
0.12
uM
LJP5
72
hr
1694 11356 11155 1.0180 1.0212
MCF 10A Crizotinib
0.12
uM
LJP5
72
hr
1694 10549 11155 0.9456 0.9359
MCF 10A Momelotinib
0.12
uM
LJP5
72
hr
1694 10139 11155 0.9089 0.8926
MCF 10A Dasatinib
0.12
uM
LJP5
72
hr
1694 6014 11155 0.5392 0.4566
MCF 10A Dasatinib
0.12
uM
LJP6
72
hr
1694 3709 11155 0.3325 0.2129
MCF 10A Dovitinib
0.12
uM
LJP5
72
hr
1694 9580 11155 0.8588 0.8335
MCF 10A Enzastaurin
0.12
uM
LJP5
72
hr
1694 11143 11155 0.9989 0.9987
MCF 10A Erlotinib
0.12
uM
LJP5
72
hr
1694 9664 11155 0.8664 0.8424
MCF 10A Foretinib
0.12
uM
LJP5
72
hr
1694 11382 11155 1.0203 1.0240
MCF 10A R406
0.12
uM
LJP6
72
hr
1694 11292 11155 1.0122 1.0144
MCF 10A Pictilisib
0.12
uM
LJP6
72
hr
1694 9285 11155 0.8323 0.8023
MCF 10A Gefitinib
0.12
uM
LJP6
72
hr
1694 6990 11155 0.6266 0.5598
MCF 10A Geldanamycin
0.12
uM
LJP5
72
hr
1694 1651 11155 0.1481 -0.0045
MCF 10A Geldanamycin
0.12
uM
LJP6
72
hr
1694 1293 11155 0.1160 -0.0423
MCF 10A GSK1059615
0.12
uM
LJP5
72
hr
1694 10702 11155 0.9593 0.9521
MCF 10A GSK1059615
0.12
uM
LJP6
72
hr
1694 9624 11155 0.8627 0.8382
MCF 10A GSK1904529A
0.12
uM
LJP6
72
hr
1694 7248 11155 0.6497 0.5870
MCF 10A Omipalisib
0.12
uM
LJP6
72
hr
1694 1837 11155 0.1647 0.0151
MCF 10A GSK 690693
0.12
uM
LJP5
72
hr
1694 11154 11155 0.9999 0.9998