LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF7 AZD-6482
0.04
uM
LJP5
 72
hr
 1389 6084 5667 1.0734 1.0972
MCF7 AZD7762
0.04
uM
LJP6
 72
hr
 1389 1987 5667 0.3506 0.1397
MCF7 AZD8055
0.04
uM
LJP6
 72
hr
 1389 1577 5667 0.2784 0.0441
MCF7 AZD8330
0.04
uM
LJP5
 72
hr
 1389 2293 5667 0.4047 0.2114
MCF7 Barasertib
0.04
uM
LJP5
 72
hr
 1389 2234 5667 0.3942 0.1975
MCF7 BI-2536
0.04
uM
LJP6
 72
hr
 1389 1537 5667 0.2712 0.0347
MCF7 BMS345541
0.04
uM
LJP6
 72
hr
 1389 5438 5667 0.9595 0.9464
MCF7 SNS-032
0.04
uM
LJP6
 72
hr
 1389 1491 5667 0.2632 0.0240
MCF7 GDC-0980
0.04
uM
LJP5
 72
hr
 1389 2176 5667 0.3840 0.1840
MCF7 NVP-AEW541
0.04
uM
LJP5
 72
hr
 1389 5919 5667 1.0443 1.0587
MCF7 SB590885
0.04
uM
LJP5
 72
hr
 1389 5303 5667 0.9356 0.9147
MCF7 PIK-93
0.04
uM
LJP5
 72
hr
 1389 6398 5667 1.1288 1.1706
MCF7 KIN001-043
0.04
uM
LJP6
 72
hr
 1389 5537 5667 0.9770 0.9696
MCF7 Alpelisib
0.04
uM
LJP5
 72
hr
 1389 5602 5667 0.9884 0.9846
MCF7 Luminespib
0.04
uM
LJP5
 72
hr
 1389 1470 5667 0.2594 0.0190
MCF7 A443654
0.04
uM
LJP6
 72
hr
 1389 1385 5667 0.2445 -0.0008
MCF7 OSI-027
0.04
uM
LJP6
 72
hr
 1389 5485 5667 0.9677 0.9573
MCF7 XMD11-85h
0.04
uM
LJP6
 72
hr
 1389 3914 5667 0.6906 0.5902
MCF7 HG-6-64-01
0.04
uM
LJP6
 72
hr
 1389 6450 5667 1.1380 1.1828
MCF7 WH-4-025
0.04
uM
LJP5
 72
hr
 1389 5576 5667 0.9838 0.9785
MCF7 WZ-4-145
0.04
uM
LJP6
 72
hr
 1389 3933 5667 0.6940 0.5947
MCF7 XMD16-144
0.04
uM
LJP5
 72
hr
 1389 2076 5667 0.3663 0.1605
MCF7 Brivanib
0.04
uM
LJP5
 72
hr
 1389 5347 5667 0.9434 0.9250
MCF7 Buparlisib
0.04
uM
LJP5
 72
hr
 1389 5379 5667 0.9490 0.9325
MCF7 BX-912
0.04
uM
LJP5
 72
hr
 1389 4745 5667 0.8372 0.7843