LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF7 WZ-4-145
0.37
uM
LJP6
 72
hr
 1389 3794 5667 0.6694 0.5621
MCF7 XMD16-144
0.37
uM
LJP5
 72
hr
 1389 1804 5667 0.3183 0.0970
MCF7 Brivanib
0.37
uM
LJP5
 72
hr
 1389 5637 5667 0.9946 0.9929
MCF7 Buparlisib
0.37
uM
LJP5
 72
hr
 1389 2134 5667 0.3765 0.1741
MCF7 BX-912
0.37
uM
LJP5
 72
hr
 1389 5266 5667 0.9291 0.9061
MCF7 Canertinib
0.37
uM
LJP6
 72
hr
 1389 4622 5667 0.8156 0.7557
MCF7 Celastrol
0.37
uM
LJP6
 72
hr
 1389 3634 5667 0.6412 0.5247
MCF7 CGP60474
0.37
uM
LJP5
 72
hr
 1389 465 5667 0.0820 -0.2160
MCF7 CGP60474
0.37
uM
LJP6
 72
hr
 1389 618 5667 0.1091 -0.1801
MCF7 CHIR-99021
0.37
uM
LJP6
 72
hr
 1389 4034 5667 0.7118 0.6183
MCF7 CP724714
0.37
uM
LJP5
 72
hr
 1389 4622 5667 0.8156 0.7557
MCF7 CP466722
0.37
uM
LJP5
 72
hr
 1389 5956 5667 1.0509 1.0674
MCF7 Crizotinib
0.37
uM
LJP5
 72
hr
 1389 4205 5667 0.7420 0.6582
MCF7 Momelotinib
0.37
uM
LJP5
 72
hr
 1389 5393 5667 0.9516 0.9359
MCF7 Dasatinib
0.37
uM
LJP5
 72
hr
 1389 1080 5667 0.1906 -0.0722
MCF7 Dasatinib
0.37
uM
LJP6
 72
hr
 1389 1028 5667 0.1814 -0.0844
MCF7 Dovitinib
0.37
uM
LJP5
 72
hr
 1389 4890 5667 0.8628 0.8183
MCF7 Enzastaurin
0.37
uM
LJP5
 72
hr
 1389 6125 5667 1.0806 1.1068
MCF7 Erlotinib
0.37
uM
LJP5
 72
hr
 1389 6206 5667 1.0949 1.1258
MCF7 Foretinib
0.37
uM
LJP5
 72
hr
 1389 1881 5667 0.3320 0.1151
MCF7 R406
0.37
uM
LJP6
 72
hr
 1389 5010 5667 0.8840 0.8464
MCF7 Pictilisib
0.37
uM
LJP6
 72
hr
 1389 1601 5667 0.2825 0.0496
MCF7 Gefitinib
0.37
uM
LJP6
 72
hr
 1389 5783 5667 1.0203 1.0269
MCF7 Geldanamycin
0.37
uM
LJP5
 72
hr
 1389 1509 5667 0.2662 0.0280
MCF7 Geldanamycin
0.37
uM
LJP6
 72
hr
 1389 1401 5667 0.2472 0.0028