LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | BI-2536 | 3.33 | uM | LJP6 | 72 | hr | 1694 | 1239 | 11155 | 0.1111 | -0.0481 |
MCF 10A | BMS345541 | 3.33 | uM | LJP6 | 72 | hr | 1694 | 10317 | 11155 | 0.9249 | 0.9114 |
MCF 10A | SNS-032 | 3.33 | uM | LJP6 | 72 | hr | 1694 | 308 | 11155 | 0.0276 | -0.1465 |
MCF 10A | GDC-0980 | 3.33 | uM | LJP5 | 72 | hr | 1694 | 2387 | 11155 | 0.2140 | 0.0733 |
MCF 10A | NVP-AEW541 | 3.33 | uM | LJP5 | 72 | hr | 1694 | 8576 | 11155 | 0.7688 | 0.7274 |
MCF 10A | SB590885 | 3.33 | uM | LJP5 | 72 | hr | 1694 | 10851 | 11155 | 0.9727 | 0.9678 |
MCF 10A | PIK-93 | 3.33 | uM | LJP5 | 72 | hr | 1694 | 9476 | 11155 | 0.8494 | 0.8225 |
MCF 10A | KIN001-043 | 3.33 | uM | LJP6 | 72 | hr | 1694 | 9973 | 11155 | 0.8940 | 0.8751 |
MCF 10A | Alpelisib | 3.33 | uM | LJP5 | 72 | hr | 1694 | 8246 | 11155 | 0.7392 | 0.6925 |
MCF 10A | Luminespib | 3.33 | uM | LJP5 | 72 | hr | 1694 | 1335 | 11155 | 0.1197 | -0.0379 |
MCF 10A | A443654 | 3.33 | uM | LJP6 | 72 | hr | 1694 | 848 | 11155 | 0.0761 | -0.0894 |
MCF 10A | OSI-027 | 3.33 | uM | LJP6 | 72 | hr | 1694 | 3517 | 11155 | 0.3153 | 0.1927 |
MCF 10A | XMD11-85h | 3.33 | uM | LJP6 | 72 | hr | 1694 | 10639 | 11155 | 0.9537 | 0.9454 |
MCF 10A | HG-6-64-01 | 3.33 | uM | LJP6 | 72 | hr | 1694 | 7100 | 11155 | 0.6365 | 0.5714 |
MCF 10A | WH-4-025 | 3.33 | uM | LJP5 | 72 | hr | 1694 | 4329 | 11155 | 0.3881 | 0.2785 |
MCF 10A | WZ-4-145 | 3.33 | uM | LJP6 | 72 | hr | 1694 | 8411 | 11155 | 0.7540 | 0.7099 |
MCF 10A | XMD16-144 | 3.33 | uM | LJP5 | 72 | hr | 1694 | 2238 | 11155 | 0.2006 | 0.0575 |
MCF 10A | Brivanib | 3.33 | uM | LJP5 | 72 | hr | 1694 | 7914 | 11155 | 0.7095 | 0.6574 |
MCF 10A | Buparlisib | 3.33 | uM | LJP5 | 72 | hr | 1694 | 1798 | 11155 | 0.1612 | 0.0110 |
MCF 10A | BX-912 | 3.33 | uM | LJP5 | 72 | hr | 1694 | 2250 | 11155 | 0.2018 | 0.0588 |
MCF 10A | Canertinib | 3.33 | uM | LJP6 | 72 | hr | 1694 | 2228 | 11155 | 0.1998 | 0.0565 |
MCF 10A | Celastrol | 3.33 | uM | LJP6 | 72 | hr | 1694 | 403 | 11155 | 0.0361 | -0.1365 |
MCF 10A | CGP60474 | 3.33 | uM | LJP5 | 72 | hr | 1694 | 466 | 11155 | 0.0418 | -0.1298 |
MCF 10A | CGP60474 | 3.33 | uM | LJP6 | 72 | hr | 1694 | 279 | 11155 | 0.0251 | -0.1495 |
MCF 10A | CHIR-99021 | 3.33 | uM | LJP6 | 72 | hr | 1694 | 10634 | 11155 | 0.9533 | 0.9449 |