LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A BI-2536
3.33
uM
LJP6
72
hr
1694 1239 11155 0.1111 -0.0481
MCF 10A BMS345541
3.33
uM
LJP6
72
hr
1694 10317 11155 0.9249 0.9114
MCF 10A SNS-032
3.33
uM
LJP6
72
hr
1694 308 11155 0.0276 -0.1465
MCF 10A GDC-0980
3.33
uM
LJP5
72
hr
1694 2387 11155 0.2140 0.0733
MCF 10A NVP-AEW541
3.33
uM
LJP5
72
hr
1694 8576 11155 0.7688 0.7274
MCF 10A SB590885
3.33
uM
LJP5
72
hr
1694 10851 11155 0.9727 0.9678
MCF 10A PIK-93
3.33
uM
LJP5
72
hr
1694 9476 11155 0.8494 0.8225
MCF 10A KIN001-043
3.33
uM
LJP6
72
hr
1694 9973 11155 0.8940 0.8751
MCF 10A Alpelisib
3.33
uM
LJP5
72
hr
1694 8246 11155 0.7392 0.6925
MCF 10A Luminespib
3.33
uM
LJP5
72
hr
1694 1335 11155 0.1197 -0.0379
MCF 10A A443654
3.33
uM
LJP6
72
hr
1694 848 11155 0.0761 -0.0894
MCF 10A OSI-027
3.33
uM
LJP6
72
hr
1694 3517 11155 0.3153 0.1927
MCF 10A XMD11-85h
3.33
uM
LJP6
72
hr
1694 10639 11155 0.9537 0.9454
MCF 10A HG-6-64-01
3.33
uM
LJP6
72
hr
1694 7100 11155 0.6365 0.5714
MCF 10A WH-4-025
3.33
uM
LJP5
72
hr
1694 4329 11155 0.3881 0.2785
MCF 10A WZ-4-145
3.33
uM
LJP6
72
hr
1694 8411 11155 0.7540 0.7099
MCF 10A XMD16-144
3.33
uM
LJP5
72
hr
1694 2238 11155 0.2006 0.0575
MCF 10A Brivanib
3.33
uM
LJP5
72
hr
1694 7914 11155 0.7095 0.6574
MCF 10A Buparlisib
3.33
uM
LJP5
72
hr
1694 1798 11155 0.1612 0.0110
MCF 10A BX-912
3.33
uM
LJP5
72
hr
1694 2250 11155 0.2018 0.0588
MCF 10A Canertinib
3.33
uM
LJP6
72
hr
1694 2228 11155 0.1998 0.0565
MCF 10A Celastrol
3.33
uM
LJP6
72
hr
1694 403 11155 0.0361 -0.1365
MCF 10A CGP60474
3.33
uM
LJP5
72
hr
1694 466 11155 0.0418 -0.1298
MCF 10A CGP60474
3.33
uM
LJP6
72
hr
1694 279 11155 0.0251 -0.1495
MCF 10A CHIR-99021
3.33
uM
LJP6
72
hr
1694 10634 11155 0.9533 0.9449