LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | SB590885 | 1.11 | uM | LJP5 | 72 | hr | 765 | 3789 | 3124 | 1.2129 | 1.2819 |
| Hs 578T | PIK-93 | 1.11 | uM | LJP5 | 72 | hr | 765 | 2970 | 3124 | 0.9508 | 0.9348 |
| Hs 578T | KIN001-043 | 1.11 | uM | LJP6 | 72 | hr | 765 | 3046 | 3124 | 0.9750 | 0.9669 |
| Hs 578T | Alpelisib | 1.11 | uM | LJP5 | 72 | hr | 765 | 2571 | 3124 | 0.8231 | 0.7657 |
| Hs 578T | Luminespib | 1.11 | uM | LJP5 | 72 | hr | 765 | 700 | 3124 | 0.2241 | -0.0274 |
| Hs 578T | A443654 | 1.11 | uM | LJP6 | 72 | hr | 765 | 397 | 3124 | 0.1271 | -0.1560 |
| Hs 578T | OSI-027 | 1.11 | uM | LJP6 | 72 | hr | 765 | 1560 | 3124 | 0.4995 | 0.3372 |
| Hs 578T | XMD11-85h | 1.11 | uM | LJP6 | 72 | hr | 765 | 2861 | 3124 | 0.9158 | 0.8885 |
| Hs 578T | HG-6-64-01 | 1.11 | uM | LJP6 | 72 | hr | 765 | 1522 | 3124 | 0.4871 | 0.3208 |
| Hs 578T | WH-4-025 | 1.11 | uM | LJP5 | 72 | hr | 765 | 450 | 3124 | 0.1442 | -0.1332 |
| Hs 578T | WZ-4-145 | 1.11 | uM | LJP6 | 72 | hr | 765 | 1579 | 3124 | 0.5055 | 0.3451 |
| Hs 578T | XMD16-144 | 1.11 | uM | LJP5 | 72 | hr | 765 | 821 | 3124 | 0.2630 | 0.0240 |
| Hs 578T | Brivanib | 1.11 | uM | LJP5 | 72 | hr | 765 | 2968 | 3124 | 0.9500 | 0.9338 |
| Hs 578T | Buparlisib | 1.11 | uM | LJP5 | 72 | hr | 765 | 698 | 3124 | 0.2236 | -0.0281 |
| Hs 578T | BX-912 | 1.11 | uM | LJP5 | 72 | hr | 765 | 1515 | 3124 | 0.4849 | 0.3178 |
| Hs 578T | Canertinib | 1.11 | uM | LJP6 | 72 | hr | 765 | 2927 | 3124 | 0.9368 | 0.9163 |
| Hs 578T | Celastrol | 1.11 | uM | LJP6 | 72 | hr | 765 | 1725 | 3124 | 0.5523 | 0.4071 |
| Hs 578T | CGP60474 | 1.11 | uM | LJP5 | 72 | hr | 765 | 395 | 3124 | 0.1266 | -0.1566 |
| Hs 578T | CGP60474 | 1.11 | uM | LJP6 | 72 | hr | 765 | 410 | 3124 | 0.1313 | -0.1503 |
| Hs 578T | CHIR-99021 | 1.11 | uM | LJP6 | 72 | hr | 765 | 2680 | 3124 | 0.8579 | 0.8119 |
| Hs 578T | CP724714 | 1.11 | uM | LJP5 | 72 | hr | 765 | 3123 | 3124 | 0.9995 | 0.9994 |
| Hs 578T | CP466722 | 1.11 | uM | LJP5 | 72 | hr | 765 | 3313 | 3124 | 1.0605 | 1.0802 |
| Hs 578T | Crizotinib | 1.11 | uM | LJP5 | 72 | hr | 765 | 2701 | 3124 | 0.8646 | 0.8206 |
| Hs 578T | Momelotinib | 1.11 | uM | LJP5 | 72 | hr | 765 | 2178 | 3124 | 0.6972 | 0.5990 |
| Hs 578T | Dasatinib | 1.11 | uM | LJP5 | 72 | hr | 765 | 501 | 3124 | 0.1605 | -0.1118 |